Publications by authors named "Mar Llorente"
Article Synopsis
- Thomas Malthus, a prominent English professor and founder of modern demography, is noted for his orofacial cleft and its unclear surgical correction history.
- An 1833 portrait by John Linnell suggests that Malthus did not have visible scarring on his upper lip, indicating a potential successful surgery, though the timeline remains uncertain.
- Despite the technical feasibility of cleft lip surgery in the 19th century, Malthus chose not to risk surgery shortly before his death, while Linnell cleverly concealed Malthus' deformity in the portrait.
Maintenance therapy with vinflunine plus best supportive care versus best supportive care alone in patients with advanced urothelial carcinoma with a response after first-line chemotherapy (MAJA; SOGUG 2011/02): a multicentre, randomised, controlled, open-label, phase 2 trial.
Jesus García-Donas Albert Font Begoña Pérez-Valderrama José Antonio Virizuela Miquel Ángel Climent Maria Del Mar Llorente
Lancet Oncol
May 2017
Background: Maintenance therapy improves outcomes in various tumour types, but cumulative toxic effects limit the choice of drugs. We investigated whether maintenance therapy with vinflunine would delay disease progression in patients with advanced urothelial carcinoma who had achieved disease control with first-line chemotherapy.
Methods: We did a randomised, controlled, open-label, phase 2 trial in 21 Spanish hospitals.