Publications by authors named "Mar Genis Girones"
Aims: A Markov model was adapted to assess the real-world cost-effectiveness of rivaroxaban, dabigatran and apixaban. Each of these non-vitamin K antagonist oral anticoagulants was compared with vitamin K antagonist for stroke prevention in patients with non-valvular atrial fibrillation in Spain.
Methods: All inputs were derived from real-world studies: baseline patient characteristics, clinical event rates, as well as persistence rates for the vitamin K antagonist treatment option.
Epidemiology of atrial fibrillation-related ischemic stroke and its association with DOAC uptake in Spain: first national population-based study 2005 to 2018.
Jaime Díaz-Guzmán Román Freixa-Pamias Javier García-Alegría Alejandro-Isidoro Pérez Cabeza Inmaculada Roldán-Rabadán
Rev Esp Cardiol (Engl Ed)
June 2022
Article Synopsis
- Atrial fibrillation (AF) has become more common, increasing the risk of strokes, but recent studies indicate that the use of direct oral anticoagulants (DOACs) may be reducing stroke rates related to AF in Spain.
- The study used data from the Spanish Ministry of Health to analyze the relationship between DOAC use and AF-related ischemic strokes in patients aged 65 and older, using statistical models for analysis.
- Results showed that before DOACs were widely used, the incidence of AF-related strokes rose, but after their introduction, rates stabilized or slightly decreased, indicating that higher DOAC uptake may positively impact health outcomes for AF patients.