Linezolid-induced lactic acidosis.

Linezolid is a commonly prescribed antibiotic in clinical practice. Although thrombocytopenia and peripheral neuropathy are frequently encountered following prolonged administration of linezolid, lactic acidosis is a rare adverse drug reaction. We present the case of a patient on linezolid for disseminated multidrug-resistant tuberculosis who presented with vomiting, dyspnoea, hypotension and high anion gap metabolic acidosis.

Peritoneal Dialysis-Related Recurrent Rhodococcus corynebacterioides Peritonitis: A Case Report and Review of Literature.

is a Gram-positive bacterium known to cause bacteremia and oligoarthritis. There have been only a few case reports in the literature that describe its association with peritoneal dialysis (PD)-related peritonitis. We report a case of recurrent peritonitis caused by .

Recent advancements in surface modifications of dental implants.

Objective: Implantology is one of the most investigated topics in modern dentistry. The current review was planned to systematically summarise all industrial, mass production and experimental trends in dental implant manufacturing relative primarily to their surface modification conducted between January 2017 and January 2020.

Materials And Methods: The review was conducted in Army Medical College, National University of Medical Sciences, Rawalpindi, Armed Forces Institute Of Dentistry, Combined Military Hospital, Rawalpindi, Foundation University College of Dentistry, Fauji Foundation Hospital, Islamabad, and the Higher Education Commission Library, Islamabad.

Synthesis, characterization and evaluation of antidengue activity of enantiomeric Schiff bases derived from S-substituted dithiocarbazate.

A series of Schiff bases have been successfully synthesized through the acid-catalyzed condensation of S-substituted dithiocarbazates and three enantiomerically pure monoterpenes, (1 )-(+)-camphor, (1 )-(-)-camphor, (1 )-(-)-camphorquinone, (1 )-(+)-camphorquinone, ( )-(-)-carvone and ( )-(+)-carvone. Spectroscopic results revealed that the Schiff bases containing camphor or carvone likely adopted an -configuration along the characteristic imine bond while those containing camphorquinone assumed a -configuration. The antidengue potential of these compounds was evaluated based on DENV 2 caused cytopathic effect (CPE) reduction-based in vitro evaluation.