A MOF nanozyme-mediated acetylcholinesterase-free colorimetric strategy for direct detection of organophosphorus pesticides.

Although some simple and rapid colorimetric methods have been developed to detect organophosphorus pesticides (OPs), the difficult extraction and easy denaturation of acetylcholinesterase (AChE) are still drawbacks needing to be overcome. Here, we propose a MOF nanozyme-mediated AChE-free colorimetric strategy for the direct detection of OPs. In the presence of OPs (pirimiphos-methyl as a model), the intense blue of oxidized 3,3',5,5'-tetramethylbenzidine (TMB) becomes light due to the quenching effect of OPs towards hydroxyl radicals (˙OH) that are generated by the decomposition of HO catalyzed by the CuCo ZIF nanozyme with excellent peroxidase (POD)-like activity.

Functional Zonation Strategy of Heterodimer Nanozyme for Multiple Chemiluminescence Imaging Immunoassay.

Although nanozymes with intrinsic enzyme-like characteristics have aroused great interest in the biosensing field, the challenge is to keep high enzyme-like activity of the nanozyme after the modification of biomolecules onto nanozymes. Herein, a functional zonation strategy of a heterodimer nanozyme was proposed to tackle the challenge and further construct a multiple chemiluminescence (CL) imaging immunoassay. Here FeO-Au as a heterodimer nanozyme model was divided into two zones, in which FeO nanoparticles (NPs) were regarded as a nanozyme zone and AuNPs were defined as an antibody immobilization zone.

Facial attractiveness is more associated with individual warmth than with competence: Behavioral and neural evidence.

Individuals appear to infer others' psychological characteristics according to facial attractiveness and these psychological characteristics can be classified into two categories in social cognition, that is, warmth and competence. However, which category of psychological characteristic is more associated with face attractiveness and its neural mechanisms have not been explored. To address this, participants were asked to judge others' warmth and competence traits based on face attractiveness, while their brains were scanned using functional magnetic resonance imaging (fMRI).

Neural processing of the physical attractiveness stereotype: Ugliness is bad vs. beauty is good.

The physical attractiveness stereotype (PAS) is characterized by the belief that beauty is good and ugliness is bad. Although the belief is not encouraged, people still express "beauty is good" explicitly. However, expressing that ugliness is bad is considered impolite in public.

Positive representation of relational self-esteem versus personal self-esteem in Chinese with interdependent self-construal.

Recent research has shown that relational self-esteem (RSE) carries important implications, especially in collectivistic cultures. In the present study, we aimed to investigate the neural mechanism underlying RSE and the behavioral and neural differences between RSE and personal self-esteem (PSE) in Chinese with interdependent self-construal. In Study 1, 581 participants completed a scale measuring RSE, the Rosenberg Personal Self-esteem Scale, and the Self-construal Scale.

Brain regions in response to character feedback associated with the state self-esteem.

Research on the Sociometer theory of self-esteem have demonstrated that manipulations of interpersonal appraisal reliably influence an individual's state self-esteem and that state levels of self-esteem correlate very highly with perceived acceptance and rejection. However, how social feedback from different sources (e.g.

Activations of the dorsolateral prefrontal cortex and thalamus during agentic self-evaluation are negatively associated with trait self-esteem.

Individual self-esteem is dominated more by agency than by communion. However, prior research has mainly focused on one's agentic/communal self-evaluation, while little is known about how one endorses others' agentic/communal evaluation of the self. The present study investigated the associations between trait self-esteem and fundamental dimensions of social cognition, i.