Publications by authors named "Maoxiang Wang"

We construct a multi-stage cell lineage model for cell division, apoptosis and movement. Cells are assumed to secrete and respond to negative feedback molecules which act as a control on the stem cell divisions (including self-renewal, asymmetrical cell division (ACD) and differentiation). The densities of cells and molecules are described by coupled reaction-diffusion partial differential equations, and the plane wavefront propagation speeds can be obtained analytically and verified numerically.

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We construct a multi-stage cell lineage model including self-renewal, apoptosis, cell movement and the symmetrical/asymmetrical division of stem cells. The evolution of cell populations can be described by coupled reaction-diffusion partial differential equations, and the propagating wavefront speeds can be obtained analytically and verified by numerical solutions of the equations. The emphasis is on the effect of symmetric/asymmetric division of stem cells on the population and propagating dynamics of cell lineage.

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In the era of the knowledge economy that is filled with intense competition, formal closed innovation can no longer meet the market demand. The enterprise needs to implement open innovation involving external resources. The concept of open innovation emphasizes both the use of internal and external resources in the process of enterprise innovation and the use of internal and external markets to promote the commercial application of innovation achievements.

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α-Sn is a topologically nontrivial semimetal in its natural structure. Upon compressively strained in plane, it transforms into a topological insulator. But, up to now, a clear and systematic understanding of the topological surface mode of topological insulating α-Sn is still lacking.

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Identifying the mechanism of intercellular feedback regulation is critical for the basic understanding of tissue growth control in organisms. In this paper, we analyze a tissue growth model consisting of a single lineage of two cell types regulated by negative feedback signaling molecules that undergo spatial diffusion. By deriving the fixed points for the uniform steady states and carrying out linear stability analysis, phase diagrams are obtained analytically for arbitrary parameters of the model.

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In this paper, through Rosenzweig-MacArthur predator-prey model we study the cyclic coexistence and stationary coexistence and discuss temporal keep and break in the food chain with two species. Then species' diffusion is considered and its effect on oscillation and stability of the ODE system is studied concerning the two different states of coexistence. We find in cyclic coexistence temporal oscillation of population is translated into spatial oscillation although there is fluctuation at the beginning of population waves and finally more stable population evolution is observed.

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The population dynamics of two interacting species modeled by the Lotka-Volterra (LV) model with general parameters that can promote or suppress the other species is studied. It is found that the properties of the two species' isoclines determine the interaction of species, leading to six regimes in the phase diagram of interspecies interaction; i.e.

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We consider the interplay of cell proliferation, cell differentiation (and de-differentiation), cell movement, and the effect of feedback regulations on the population and propagation dynamics of different cell types in a cell lineage model. Cells are assumed to secrete and respond to negative feedback molecules which act as a control on the cell lineage. The cell densities are described by coupled reaction-diffusion partial differential equations, and the propagating wave front solutions in one dimension are investigated analytically and by numerical solutions.

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We construct a model for cell proliferation with differentiation into different cell types, allowing backward de-differentiation and cell movement. With different cell types labeled by state variables, the model can be formulated in terms of the associated transition probabilities between various states. The cell population densities can be described by coupled reaction-diffusion partial differential equations, allowing steady wavefront propagation solutions.

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The folding process of a single chain including coil-globule transition and crystallization has been investigated through dynamic Monte Carlo simulations. The results based upon ensemble averaging illustrated three distinct states: coil, molten globule, and globule states. Furthermore, the crystallization process from these collapsed states demonstrated various characteristics and it also verified the thermodynamic partitions.

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We consider the competitive population dynamics of two species described by the Lotka-Volterra model in the presence of spatial diffusion. The model is described by the diffusion coefficient (d(α)) and proliferation rate (r(α)) of the species α (α = 1,2 is the species label). Propagating wave front solutions in one dimension are investigated analytically and by numerical solutions.

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We studied athermal relaxation of bulk extended chains by means of dynamic Monte Carlo simulations, and we got intermediately relaxed melts with a memory of chain orientations but no more crystalline order. The orientational memory in the melts dominated the crystal orientation and nucleation types. The difference in crystallization behaviors induced by orientational relaxation suggested the mechanism of hierarchical crystallization.

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We report dynamic Monte Carlo simulations of polymer crystallization confined in the cylindrical microdomains of diblock copolymers. The microdomains were prepared via spontaneous microphase separation from homogeneous melt, and the major component was then frozen in a vitreous amorphous state to make a hard confinement to the crystallization of the minor component. We found that during the isothermal crystallization at high temperatures, crystal orientations are dominantly perpendicular to the cylinder axis at the early stage of crystal nucleation and remain to the final state; while if the block junctions are broken before crystallization, crystal orientations are dominantly parallel at the early stage of crystal nucleation, and eventually other orientations take the place of parallel preferences.

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