Clinical Analysis of Myocardial Injury in Highlanders with Pulmonary Hypertension.

Pulmonary hypertension (PH) is a prevalent adverse cardiovascular event at high-altitude environments. Prolonged exposure to high altitudes may result in myocardial injury, which is associated with poor clinical outcomes. This study aims to investigate the clinical characteristics of myocardial injury in patients with PH at high altitude.

The cardiovascular system at high altitude: A bibliometric and visualization analysis.

Background: When exposed to high-altitude environments, the cardiovascular system undergoes various changes, the performance and mechanisms of which remain controversial.

Aim: To summarize the latest research advancements and hot research points in the cardiovascular system at high altitude by conducting a bibliometric and visualization analysis.

Methods: The literature was systematically retrieved and filtered using the Web of Science Core Collection of Science Citation Index Expanded.

Association of body mass index with clinical outcomes in patients with acute coronary syndrome: A systematic review and meta-analysis.

Background: In this meta-analysis, we aimed to systematically examine the relationship between body mass index and major adverse cardiovascular events in acute coronary syndrome patients and to provide theoretical guidance for body weight management in these patients.

Methods: A comprehensive analysis of applicable research published between 2008 and 2021 was conducted using the PubMed, Cochrane, Web of Science, Wanfang, and CNKI databases. Extracted odds ratios from the randomized-controlled studies were pooled using fixed-effects meta-analysis.

Microplastic enrichment capacity of Ctenochaetus striatus from the habitat environment - An example in Xisha, South China Sea.

Microplastic pollution is a widespread concern in the global marine environment. In this study, microplastic pollution status in Xisha waters was investigated. Microplastics were found in all seawater samples, and 90.

Study on the Geographic Variation and Trophic Variation of in Different Areas Based on Stable Isotope Information from the Gladius.

The Japanese flying squid () is an important cephalopod in the northwest Pacific Ocean. In this study, the proostracum of the gladius of samples collected by Chinese squid fishing vessels in the East China Sea and the Sea of Japan in August and December 2018 were continuously cut, and stable isotope values of the cut fragments were used to analyze the migration path and feeding ecology of . The results showed that when the proostracum grew to 120 mm from the distal end, began to migrate.

Pulmonary arterial hypertension associated with congenital heart disease: An omics study.

Pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) is a severely progressive condition with uncertain physiological course. Hence, it has become increasingly relevant to clarify the specific mechanisms of molecular modification, which is crucial to identify more treatment strategies. With the rapid development of high-throughput sequencing, omics technology gives access to massive experimental data and advanced techniques for systems biology, permitting comprehensive assessment of disease occurrence and progression.

Theoretical modeling and investigations of lossy mode resonance prism sensor based on TiO film.

The optical sensor based on lossy mode resonance can overcome the limitations of traditional surface plasmon resonance sensors and work under TE and TM polarized light. In this paper, an LMR sensor theoretical model with the configuration of prism/matching layer/lossy layer/sensing layer is proposed, which is based on the principle of attenuated total reflection. By using TiO film as the lossy layer and LiF film as the matching layer, the resonance signal under angle interrogation is effectively improved.

Effect of Cerium Oxide Nanoparticles on Myocardial Cell Apoptosis Induced by Myocardial Ischemia-Reperfusion Injury.

This study was to provide a theoretical basis for effective treatment of myocardial ischemia-reperfusion injury (I/R injury) and explore the effect of cerium oxide (CeO2) nanoparticles on myocardial cell apoptosis induced by I/R injury. In this study, 50 healthy male Sprague Dawley (SD) rats were selected and divided into five groups according to the random table method: a sham operation group, an I/R group, a 1 - 10 nm CeO2 nanoparticle group (CeO2-1 group), a 10 - 25 nm CeO2 nanoparticle group (CeO2-2 group), and a 50 nm CeO2 nanoparticle group (CeO2-3 group). Rats in different groups were injected with phosphate buffer solution (PBS) and CeO2 nanoparticles with different diameters, respectively.

Ultra-Broadband Tunable Terahertz Metamaterial Absorber Based on Double-Layer Vanadium Dioxide Square Ring Arrays.

Based on the phase transition of vanadium dioxide(VO), an ultra-broadband tunable terahertz metamaterial absorber is proposed. The absorber consists of bilayer VO square ring arrays with different sizes, which are completely wrapped in Topas and placed on gold substrate. The simulation results show that the absorption greater than 90% has frequencies ranging from 1.

Self-referenced refractive index sensor based on double-dips method with bimetal-dielectric and double-groove grating.

Self-referenced refractive index sensors allow more accurate measurements and reduce the influence of extraneous factors. This work proposed a high-sensitivity, self-referenced surface plasmon resonance sensor with Na grating and Au-ZnS composite grating. When Transverse Magnetic-polarized light is incident into the prism, three surface plasmon resonances are excited at the interface of Na-MgF grating and Au-ZnS grating.

MicroRNA-382-5p inhibits osteosarcoma development and progression by negatively regulating VEZF1 expression.

Human osteosarcoma is the most frequent malignant primary bone tumor that mainly occurs in young adults and children. MicroRNAs (miRNAs/miRs) are abnormally expressed in human osteosarcoma and contribute to osteosarcoma initiation and development. The present study aimed to investigate the role of miR-382-5p in the nosogenesis of osteosarcoma and to identify a novel target for osteosarcoma treatment.

High-throughput mining of E-genome-specific SNPs for characterizing Thinopyrum elongatum introgressions in common wheat.

Diploid Thinopyrum elongatum (EE, 2n = 2x = 14) and related polyploid species constitute an important gene pool for improving Triticeae grain and forage crops. However, the genomic and molecular marker resources are generally poor for these species. To aid the genetic, molecular, breeding and ecological studies involving Thinopyrum species, we developed a strategy for mining and validating E-genome-specific SNPs using Th.

Construction and characterization of the transformation-competent artificial chromosome (TAC) libraries of Leymus multicaulis.

Transformation-competent artificial chromosome system is able to clone and transfer genes efficiently in plants. In order to clone genes highly tolerant to barley yellow dwarf virus (BYDV), Aphids, drought and salt from Leymus multicaulis, the two TAC genomic libraries I and II were constructed in vector pYLTAC17 and pYLTAC747H/sacB, which contain about 165000 and 236000 recombinant clones separately. The genome coverage of the two libraries was totally estimated to be about 3-5 haploid genome equivalents, as size selection of genomic DNA fragments was approximately from 9 to 300 kb.