Pump-power-controlled L-band wavelength-tunable mode-locked fiber laser utilizing nonlinear polarization evolution in all-polarization-maintaining fibers.

We present for the first time, to the best of our knowledge, the pump-power-controlled, all-polarization-maintaining (all-PM), all-fiber configured, wavelength-tunable mode-locked fiber laser in the L-band (1565 to 1625 nm). A tuning range over 20 nm (1568.2  to 1588.

[Retracted] Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway.

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the immunofluorescence staining data shown in Fig. 3C, and the migration and invasion assay data shown in Figs. 4C and 4D were strikingly similar to data appearing in different form in other research articles written by different authors at different research institutes that had either already been published, or were submitted for publication at around the same time, one of which has been retracted.

All-polarization-maintaining, efficiently wavelength-tunable, Er-doped mode-locked fiber laser with a compact reflective Lyot filter.

Wavelength tunable mode-locked fiber lasers have highly potential applications in precision spectroscopy, nonlinear microscopy and photonic sensing. Here, we present a compact and thermal-sensitive reflective Lyot filter and utilize it for all-polarization-maintaining efficiently wavelength-tunable Er-doped carbon-nanotube-mode-locked laser for the first time, to the best of our knowledge. The output wavelength of the laser can be tuned from 1544.

L-band mode-locked fiber laser using all polarization-maintaining nonlinear polarization rotation.

For the first time, to the best of our knowledge, in the soliton regime, we demonstrate an L-band fiber laser mode-locked by all polarization-maintaining (all-PM) nonlinear polarization rotation (NPR). A numerical study suggests that lengthening the NPR section boosts modulation depth and lowers saturation power of the artificial saturable absorber (SA). With the longest NPR section to date (21 m), the laser emits 1.

NF-κB p65 and SETDB1 expedite lipopolysaccharide-induced intestinal inflammation in mice by inducing IRF7/NLR-dependent macrophage M1 polarization.

Macrophages exhibit distinct phenotypes that are pro-inflammatory (M1) or anti-inflammatory (M2) in response to inflammation. In this study, we tried to identify the roles and mechanisms of interferon regulatory factor 7 (IRF7) in modulating the phenotypes of macrophages in lipopolysaccharide (LPS)-induced intestinal inflammation. The mouse model of intestinal inflammation was induced by lipopolysaccharide (LPS), and mouse bone marrow-derived macrophages (BMDMs) and mouse intestinal epithelial cells were selected for experimental verification in vitro.

FOXQ1-mediated SIRT1 upregulation enhances stemness and radio-resistance of colorectal cancer cells and restores intestinal microbiota function by promoting β-catenin nuclear translocation.

Background: Resistance of colorectal cancer (CRC) cells to radiotherapy considerably contributes to poor clinical outcomes of CRC patients. Microarray profiling in this study revealed the differentially expressed forkhead box Q1 (FOXQ1) in CRC, and thus we aimed to illustrate the role of FOXQ1 in CRC by modulating stemness and radio-resistance of CRC cells.

Methods: CRC and adjacent normal tissues were collected from CRC patients, and the correlation between FOXQ1 expression and CRC prognosis was analyzed.

Effect of remifentanil combined with sevoflurane inhalation anesthesia on coagulation function and postoperative recovery of patients undergoing endoscopic selective varices devascularization.

Objective: To investigate the effect of remifentanil combined with sevoflurane inhalation anesthesia on coagulation function and postoperative recovery of patients undergoing endoscopic selective varices devascularization (ESVD).

Methods: Altogether 116 patients undergoing ESVD in our hospital were randomly divided into two groups. The control group received propofol combined with remifentanil anesthesia, while the observation group received remifentanil combined with sevoflurane inhalation anesthesia.

Research on variation law of geophysical drill-bit downhole flow field under the interaction of multiple hydraulic factors.

Mountain geophysical prospecting operations play an important role in the entire petroleum exploration field. Geophysical drill-bit is the main tool for mountain geophysical prospecting operations. Its hydraulic structure directly affects the downhole flow field and then affects the chip removal efficiency and drilling efficiency of the bit.

Ultrasensitive temperature sensor with Vernier-effect improved fiber Michelson interferometer.

A novel fiber Michelson interferometer (FMI) based on parallel dual polarization maintaining fiber Sagnac interferometers (PMF-SIs) is proposed and experimentally demonstrated for temperature sensing. The free spectral range (FSR) difference of dual PMF-SIs determines the FSR of envelope and sensitivity of the sensor. The temperature sensitivity of parallel dual PMF-SIs is greatly enhanced by the Vernier effect.

State-of-the-Art Optical Microfiber Coupler Sensors for Physical and Biochemical Sensing Applications.

An optical fiber coupler is a simple and fundamental component for fiber optic technologies that works by reducing the fiber diameter to hundred nanometers or several micrometers. The microfiber coupler (MFC) has regained interest in optical fiber sensing in recent years. The subwavelength diameter rationales vast refractive index (RI) contrast between microfiber "core" and surrounding "cladding", a large portion of energy transmits in the form of an evanescent wave over the fiber surface that determines the MFC ultrasensitive to local environmental changes.

Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway.

Rotenone, a natural hydrophobic pesticide, has been reported to display anticancer activity in a variety of cancer cells. However, the mechanism of rotenone on colon cancer (CC) cell migration, invasion and metastasis is still unknown. In the present study, the cytotoxicity of rotenone on CC cells were detected by the Cell Counting Kit‑8 assay and confirmed by clone formation assay.