Cotteslosin D, a new cyclopentapeptide from a sponge-derived fungus 2-18.

A new cyclopentapeptide, cotteslosin D (), was isolated from the cultures of a sponge-derived fungus 2-18. The structure of was eluvidated as -(-Me-L-Tyr-L-Val-L-Pro-L-Tyr-L-Phe) on the basis of extensive spectroscopic analysis and chemical methods. Compound displayed weak antibacterial activities against and .

The ameliorative and neuroprotective effects of dietary fibre on hyperuricaemia mice: a perspective from microbiome and metabolome.

The effect of single dietary fibre (DF) on lowering uric acid (UA) level has been reported in the literature. However, the potential protective mechanism of DF against potassium oxybate-induced hyperuricaemia (HUA), as modelled by prophylactic administration, remains unclear. The data demonstrate that DF significantly decreased serum and cerebral tissue UA concentrations, inhibited xanthine oxidase expression and activity in the liver and reduced levels of creatinine and urea nitrogen in the serum.

The accumulation of heavy metals in agricultural land and the associated potential ecological risks in Shenzhen, China.

Accumulation of heavy metals in agricultural land and their ecological risks are key issues in soil security studies. This study investigated the concentrations of six heavy metals--copper (Cu), zinc (Zn), lead (Pb), nickel (Ni), and chromium (Cr) in Shenzhen's agricultural lands and examined the potential hazards and possible sources of these metals. Eighty-two samples from agricultural topsoil were collected.

[Spatial distribution of soil PCBs congeners in typical area of Yangtze River Delta region].

191 surface farmland soil samples were collected from an area of 27 km2 in typical polluted county of the Yangtze River Delta region and analyzed for concentrations of 16 kinds of polychlorinated biphenyls. The results of statistical analysis indicated that the concentrations of PCBs in the soils ranged from 0.01-484.