Publications by authors named "Maojun Chen"

Background: Gliomas, particularly glioblastoma (GBM), are the most common and aggressive primary brain tumors in adults, characterized by high malignancy and frequent recurrence. Despite standard treatments, including surgery, radiotherapy, and chemotherapy, the prognosis for GBM remains poor, with a median survival of less than 15 months and a five-year survival rate below 10%. Tumor heterogeneity and resistance to treatment create significant challenges in controlling glioma progression.

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Introduction: Breast cancer has become a common tumour that threatens women's physical and mental health. Microbial agents play an important role in maintaining the balance of gut microbiota and modulating intestinal immunity, anti-inflammatory and antioxidant effects. Available evidence points to a strong association between them and breast cancer.

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The moist healing theory proves that a moderately moist and airtight environment is conducive to wound healing. However, different moist dressings have different functions. We aim to evaluate the effects of moist dressings on wound healing after surgical suturing and identify superior moist dressings.

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Objective: To evaluate the effectiveness of preoperative shaving and postoperative shampooing on the infection rate in neurosurgery.

Design: Meta-analysis.

Data Source: We conducted a search of the Embase, CINAHL, Scopus and PubMed databases up until February 1, 2022.

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Background: To investigate whether the administration of intravenous propofol before endotracheal suctioning (ES) in patients with severe brain disease can reduce the sputum suction response, improve prognosis, and accelerate recovery.

Methods: A total of 208 severe brain disease patients after craniocerebral surgery were enrolled in the study. The subjects were randomly assigned to the experimental group (n = 104) and the control group (n = 104).

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Objective: To compare the efficacy of several antiseptics in decreasing the blood culture contamination rate.

Design: Network meta-analysis.

Data Source: Electronic searches of PubMed and Embase were conducted up to November 2015.

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Objective: To investigate the clinical features and perioperational managements of craniophayngiomas located in posterior fossa.

Methods: Nine patients with craniopharyngioma situated in posterior fossa were included in the study. The clinical manifestations, neuroimage features, operational treatment, and perioperational managments were retrospectively analyzed.

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Objective: To investigate characteristics of circadian rhythm in intracerebral hemorrhage before death.

Methods: This retrospective study was carried out from September 2002 to February 2009. One hundred and twenty-two dead cases with intracerebral hemorrhage(ICH) were collected.

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