Publications by authors named "Maojie Lv"
Article Synopsis
- Rutin is a flavonoid with potential benefits for treating Alzheimer's, preventing brain damage, and combating glioblastoma, but its therapeutic use is hindered by poor solubility and limited ability to cross the blood-brain barrier (BBB).
- A new delivery system called transferrin-modified Rutin liposomes (Tf-Rutin-Lip) was developed to enhance Rutin's bioavailability and brain-targeting efficiency by incorporating transferrin into liposomes.
- Experimental results showed that Tf-Rutin-Lip liposomes can cross the BBB without damaging brain cells, demonstrating improved pharmacokinetic properties compared to standard Rutin, thus highlighting their potential as a therapeutic strategy.
() is a critical disease affecting broiler health, with as its primary pathogen. compound extract (PHCE), formulated based on traditional Chinese veterinary principles, contains primarily flavonoids with antibacterial, anti-inflammatory, and antioxidant properties. However, PHCE's efficacy against -induced and its underlying mechanism remain unclear.
View Article and Find Full Text PDFThe nucleolus is a dynamic subnuclear structure, which is crucial to the normal operation of the eukaryotic cell. The porcine epidemic diarrhea virus (PEDV), coronavirus nucleocapsid (N) protein, plays important roles in the process of virus replication and cellular infection. Virus infection and transfection showed that N protein was predominately localized in the cytoplasm, but also found in the nucleolus in Vero E6 cells.
View Article and Find Full Text PDFObjective: To elucidate the co-localization characteristic between porcine epidemic diarrhea virus (PEDV) N protein and B23.1 phosphoprotein.
Methods: Two pairs of primers used to amplify N gene and B23.