An Exploration of the Antioxidative and Anti-Inflammatory Role of 106 via Improving Mitochondrial Function.

In this present study, bioinformatics analysis and the experimental validation method were used to systematically explore the antioxidant activity and anti-inflammatory effect of A106, which was isolated from traditional Chinese pickles, on lipopolysaccharide (LPS)-induced RAW264.7 macrophages. A106 had a good scavenging ability for DPPH, ABTS, and hydroxyl radicals.

Insights into the Mechanisms of Reuterin against Based on Membrane Damage and Untargeted Metabolomics.

Reuterin is a dynamic small-molecule complex produced through glycerol fermentation by and has potential as a food biopreservative. Despite its broad-spectrum antimicrobial activity, the underlying mechanism of action of reuterin is still elusive. The present paper aimed to explore the antibacterial mechanism of reuterin and its effects on membrane damage and the intracellular metabolome of .

Speech signal enhancement based on deep learning in distributed acoustic sensing.

The fidelity of a speech signal deteriorates severely in a distributed acoustic sensing (DAS) system due to the influence of the random noise. In order to improve the measurement accuracy, we have theoretically and experimentally compared and analyzed the performance of the speech signal with and without a recognition and reconstruction method-based deep learning technique. A complex convolution recurrent network (CCRN) algorithm based on complex spectral mapping is constructed to enhance the information identification of speech signals.

Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review.

The reuterin system is a complex multi-component antimicrobial system produced by by metabolizing glycerol. The system mainly includes 3-hydroxypropionaldehyde (3-HPA, reuterin), 3-HPA dimer, 3-HPA hydrate, acrolein and 3-hydroxypropionic acid, and has great potential to be applied in the food and medical industries due to its functional versatility. It has been reported that the reuterin system possesses regulation of intestinal flora and anti-infection, anti-inflammatory and anti-cancer activities.

Research Progress in Distributed Acoustic Sensing Techniques.

Distributed acoustic sensing techniques based on Rayleigh scattering have been widely used in many applications due to their unique advantages, such as long-distance detection, high spatial resolution, and wide sensing bandwidth. In this paper, we provide a review of the recent advancements in distributed acoustic sensing techniques. The research progress and operation principles are systematically reviewed.

Antibacterial Activity of Crude Extract Against and Its Application as a Natural Disinfectant.

is an opportunistic food-borne pathogen that endangers the health of neonates and infants. This study aims to elucidate the antibacterial activity and mechanism of crude extract (CBCE) against and its application as a natural disinfectant. The antibacterial activity was evaluated by the determination of the diameter of inhibition zone (DIZ), minimum inhibitory concentration (MIC), and minimum bactericide concentration (MBC).

Pretreatment with F-9-35 attenuates ethanol-induced gastric injury in rats.

Background: Previous studies suggested that probiotics intervention may be one of the methods for preventing and/or treating gastric ulcer.

Objective: The aim of the study was to compare the preventive effects of a spaceflight mutant F-9-35 and its wild type on ethanol-induced gastric injury in rats.

Design: Forty rats were randomly allocated into five groups: a normal group (NOR), ethanol group (EtOH), skim milk group (MILK), F-9-35 group (F935) and wild-type group (WT).

The Prebiotic Activity of Simulated Gastric and Intestinal Digesta of Polysaccharides from the .

(HE) is a well-known edible and medicinal fungus widely grown in Asian countries. Polysaccharides from the (HEP) are major biological macromolecules. It has been reported that HEP has multiple biological activities, such as antioxidant activity, immunomodulatory effects, anti-inflammatory effect, anti-chronic gastritis activity, and so on.

1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.

As a common food processing pollutant, 1,3-Dichloro-2-propanol can be found in foodstuffs, especially in soup spices and instant soups. Mounting researchers have unfolded the relation between 1,3-DCP and various diseases. Autophagy is a process of self-regulation and defects in autophagy have been bound up with multifarious human pathologies and metabolic diseases.

Lactobacillus reuteri F-9-35 Prevents DSS-Induced Colitis by Inhibiting Proinflammatory Gene Expression and Restoring the Gut Microbiota in Mice.

Unlabelled: Probiotics are considered to be a potential treatment for ulcerative colitis (UC). The aim of this study was to compare the preventive effect of a space flight-induced mutant L. reuteri F-9-35 and its wild type on UC in vivo.

Alliin attenuates 1, 3-dichloro-2-propanol-induced lipogenesis in HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway.

Accumulating evidence reveals the association of 1, 3-dichloro-2-propanol (1, 3-DCP) exposure and lipogenesis. Alliin, the most abundant sulphur compound in garlic, has been demonstrated to exhibit hypoglycemic, antioxidant and anti-inflammatory activities. Here, we showed that alliin attenuated lipogenesis induced by 1,3-DCP and that the reduction was due to activation of the AMPK pathway.

Effect of a novel potential probiotic Lactobacillus paracasei Jlus66 isolated from fermented milk on nonalcoholic fatty liver in rats.

Nonalcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease worldwide. Previous evidence indicates that probiotics can be applied as a therapeutic agent for NAFLD. In this study, the potential probiotic strain Lactobacillus paracasei Jlus66 was isolated from natural fermented milk by a culture-dependent method, and its probiotic potentials were tested by established in vitro tests.

Optimization of the quenching method for metabolomics analysis of Lactobacillus bulgaricus.

This study proposed a quenching protocol for metabolite analysis of Lactobacillus delbrueckii subsp. bulgaricus. Microbial cells were quenched with 60% methanol/water, 80% methanol/glycerol, or 80% methanol/water.