Publications by authors named "Mao-yi Lin"
Article Synopsis
- A study involving 920 patients with stable angina tested the efficacy of Danhong injection (DHI), a polypharmacological drug, over 14 days, finding that DHI significantly improved patient-reported angina frequency compared to a placebo.
- There were no significant differences in major vascular events or serious side effects between the DHI and placebo groups, indicating DHI's safety in this population.
- RNA sequencing identified a new therapeutic module related to blood coagulation and cholesterol metabolism as a potential target for DHI's effects, highlighting a connection between this module and positive changes in angina symptoms.
Objective: To quantity the amount of tetramethylpyrazine in Szechwan Lovage Rhizome (Chuanxiong, the rhizome of Ligusticum chuanxiong Hort., CX) and Cnidium Rhizome(Japanese Chuanxiong, the rhizome of Cnidium officinale Makino, JCX) for quality assessment.
Methods: An HPLC-DAD-MS technique was employed to detect tetramethylpyrazine in 27 CX and 10 JCX samples.
[Study on relationship between the polymorphism of angiotensin converting enzyme gene and blood stasis syndrome in patients with coronary heart disease].
Zhongguo Zhong Xi Yi Jie He Za Zhi
September 2004
Article Synopsis
- The study investigates the link between angiotensin converting enzyme (ACE) gene polymorphism and blood stasis syndrome (BSS) in coronary heart disease (CHD) patients.
- Researchers analyzed ACE gene types and measured levels of certain biomarkers (endothelin, angiotensin II, and nitric oxide) in CHD patients with and without BSS, as well as in healthy controls.
- Results show a higher occurrence of the DD genotype of ACE in BSS patients, along with elevated levels of endothelin and angiotensin II, suggesting that this genotype may increase susceptibility to CHD in BSS patients.