Publications by authors named "Mao-Lei Sun"
miR-144-5p exhibits anti-tumor activities in various cancers. Although treatment for glioblastoma has progressed rapidly, novel targets for glioblastoma are insufficient, particularly those used in precision medicine. In the current study, we found that ginsenoside Rd reduced the proliferation and migration of glioblastoma cells.
View Article and Find Full Text PDFExpression of miR-1304 in patients with esophageal carcinoma and risk factors for recurrence.
World J Gastroenterol
February 2020
Article Synopsis
- Esophageal carcinoma is a serious cancer with poor outcomes, and the study investigates the role of a newly discovered microRNA, miR-1304, in patients with this condition.
- Researchers analyzed the expression of miR-1304 using data from The Cancer Genome Atlas and tested its levels in patient tissues and blood.
- The findings show that higher levels of miR-1304 correlate with larger tumor sizes, poorer differentiation, and worse survival rates, indicating its potential as a diagnostic and prognostic marker for esophageal carcinoma.*
Background: Oral squamous cell carcinoma (OSCC) ranks as the fifth most frequent cancer worldwide, and the recurrence and migration of OSCC still pose large threats to patients. Long non-coding RNAs (lncRNAs) have recently emerged as crucial players in cancer development, and it is of great significance to understand the regulatory nexus of lncRNAs in OSCC.
Methods: Here, we identified a novel lncRNA, RP11-874J12.
Background: Esophageal cancer is one of the most poorly diagnosed and fatal cancers in the world. Although a series of studies on esophageal cancer have been reported, the molecular pathogenesis of the disease remains elusive.
Aim: To investigate comprehensively the molecular process of esophageal cancer.