Publications by authors named "Mao Suzuki"

Background: Anti-SS-A/Ro antibody (anti-SSA), the diagnostic marker of Sjögren's syndrome (SS), is often detected in systemic sclerosis (SSc). Some patients are diagnosed with SSc/SS overlap syndromes, while there are anti-SSA-positive SSc cases without SS. In this study, we investigated the clinical characteristics of SSc with anti-SSA and clarified the clinical impact of this antibody in SSc.

View Article and Find Full Text PDF
Article Synopsis
  • Exercise-induced anaphylaxis (EIA) is a rare condition that can be challenging to diagnose, and this report presents the first known case of EIA triggered specifically by leek consumption.
  • An 18-year-old woman experienced severe allergic symptoms after exercising, leading to a series of tests that ultimately confirmed her sensitivity to leeks during physical exertion despite some tests showing no reaction.
  • The case highlights the need for thorough allergy assessments and interviews since leek allergies are very uncommon, emphasizing that uncommon allergens can play a role in EIA.
View Article and Find Full Text PDF
Article Synopsis
  • * Periostin appears to influence monocytes and macrophages, contributing to inflammation and fibrosis in SSc patients.
  • * Monocytes and macrophages from SSc patients show increased expression of pro-fibrotic factors and higher cell migration when stimulated with periostin, compared to healthy controls.
View Article and Find Full Text PDF

The [1,3]-nitrogen rearrangement reactions of -aryl ketoximes were promoted by heterocyclic carbene (NHC)-copper catalysts and BF·OEt as an additive, affording aminophenol derivatives in good yields. The reaction of substrates with electron-withdrawing substituents on the phenol moiety are accelerated by adding silver salt and modifying the substituent at the nitrogen atom. Density functional theory calculations suggest that the rate-determining step of this reaction is the oxidative addition of the N-O bond of the substrate to the copper catalyst.

View Article and Find Full Text PDF

Thyroid hormones play an important role in brain development, and thyroid hormone insufficiency during the perinatal period results in severe developmental delays. Perinatal thyroid hormone deficiency is clinically known as congenital hypothyroidism, which is caused by dysgenesis of the thyroid gland or low iodine intake. If the disorder is not diagnosed or not treated early, the neuronal architecture is perturbed by thyroid hormone insufficiency, and neuropathological findings, such as abnormal synapse formation, defects in neuronal migration, and impairment of myelination, are observed in the brains of such patients.

View Article and Find Full Text PDF
Article Synopsis
  • The gene studied encodes a protease in the thylakoid membrane, which plays a key role in chloroplast development in leaf mesophyll cells.
  • Research on two mutants derived from Ar radiation showed severe chlorophyll deficiency in chloroplasts of leaf epidermal guard and pavement cells.
  • Observations indicated that the gene is crucial for chloroplast differentiation, particularly in guard cells, as it affects the size and development of plastids.
View Article and Find Full Text PDF
Article Synopsis
  • * Metastatic renal cell carcinoma is rare in the stomatognathic region, making up only 1 to 3% of malignant tumors in that area, with even rarer instances of it affecting the oral mucosal tissue.
  • * The review emphasizes the importance of distinguishing between metastatic renal cell carcinoma and malignant salivary gland tumors due to overlapping characteristics.
View Article and Find Full Text PDF

The functional role of thyroid hormone (TH) in the cortex and hippocampus of mouse during neuronal development was investigated in this study. TH insufficiency showed a decrease in the expression of parvalbumin (PV) in the cortex and hippocampus of pups at postnatal day (PD) 14, while treatment with thyroxine from PD 0 to PD 14 ameliorated the PV loss. On the other hand, treatment with antithyroid agents in adulthood did not result in a decrease in the expression of PV in these areas.

View Article and Find Full Text PDF

Background: Non-communicable diseases (NCDs) are increasingly recognized as a significant threat to health and development globally, and United Nations (UN) Member States adopted the Political Declaration of the Third High-level Meeting (HLM) on the prevention and control of NCDs in 2018. The negotiation process for the Declaration included consultations with Member States, intergovernmental organizations (IGOs), and non-state actors such as non-governmental organizations (NGOs) and the private sector. With NCD responses facing charges of inadequacy, it is important to scrutinize the governance process behind relevant high-level global decisions and commitments.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionq3un9iqdh49v1nj1292fqctedqs628fn): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once