Comparative study of dacryocystorhinostomy with and without intraoperative application of Mitomycin C.

Aims And Objectives: To compare the outcome of dacryocystorhinostomy surgery with and without the intraoperative use of Mitomycin C.

Methods: Our study is a prospective comparative case study in which 50 patients of primary acquired nasolacrimal duct obstruction were divided on the basis of random sampling into the conventional dacryocystorhinostomy group and the Mitomycin C group in which Mitomycin C 0.2 mg/ml was used intraoperatively.

Corneal endothelial safety of intracameral preservative-free 1% xylocaine.

Purpose: To evaluate the effect of intracameral preservative-free 1% xylocaine on the corneal endothelium as an adjuvant to topical anaesthesia during phacoemulsification and Acrysof foldable IOL implantation.

Material & Methods: This is a prospective, controlled, randomised, double-masked study. 106 patients with soft to moderately dense (Grade 1-3) senile cataract and corneal endothelial cell density of >1500/mm2 were randomised to the xylocaine group (n=53) and control group(n=53).