Fire and smoke real-time detection algorithm for coal mines based on improved YOLOv8s.

Fire and smoke detection is crucial for the safe mining of coal energy, but previous fire-smoke detection models did not strike a perfect balance between complexity and accuracy, which makes it difficult to deploy efficient fire-smoke detection in coal mines with limited computational resources. Therefore, we improve the current advanced object detection model YOLOv8s based on two core ideas: (1) we reduce the model computational complexity and ensure real-time detection by applying faster convolutions to the backbone and neck parts; (2) to strengthen the model's detection accuracy, we integrate attention mechanisms into both the backbone and head components. In addition, we improve the model's generalization capacity by augmenting the data.

Preparation of reversible cross-linked amphiphilic polymeric micelles with pH-responsive behavior for smart drug delivery.

A new type of reversible cross-linked and pH-responsive polymeric micelle (PM), poly[polyethylene glycol methacrylate--2-(acetoacetoxy)ethyl methacrylate]--poly [2-(dimethylamino)ethyl methacrylate] [P(PEGMA--AEMA)--PDMAEMA], was synthesized for targeted delivery of curcumin. After reversible cross-linking of the micellar shell, the PMs with a typical core-shell structure exhibited excellent stability against extensive dilution and good reversibility of pH-responsiveness in solutions with different pH values. P(PEGMA--AEMA)--PDMAEMA has the lowest critical micelle concentration (CMC) value (0.

Exploration of Joint Optimization and Visualization of Inventory Transportation in Agricultural Logistics Based on Ant Colony Algorithm.

The problem of joint optimization of inventory and transportation in agricultural logistics and distribution is a typical logistics problem, but agricultural logistics and distribution also have their own characteristics, such as uneven distribution of outlets, complex road conditions, very many outlets, a single order with few goods but high frequency of ordering, centralized distribution, and unified channels. To promote the sustainable development of the economy, it is necessary to save energy and reduce emissions, and eventually enter a new era of "low consumption, low pollution, and low emissions." Modern logistics vehicle-scheduling process is complex and changeable, and the existing mathematical methods are not perfect in solving this problem, lacking scientific theory as a guide.

Ion-pair compounds of diacerein for enhancing skin permeability : the compatibility-permeability relationship of counter ion and diacerein.

This research aimed to investigate how the relationship between counter ion and diacerein (DCN) exerts an effect on the skin penetration of DCN ion-pair compounds. After the ion-pair compounds were formed by DCN and organic amines with different functional groups, the hydrogen bond of these compounds was confirmed by Fourier-transform infrared (FTIR) spectroscopy and molecular docking. The skin of porcine ears was employed to conduct the skin penetration, DCN - triethanolamine was the most potential candidate with the of 7.

Mesoscale Simulations of pH-Responsive Amphiphilic Polymeric Micelles for Oral Drug Delivery.

It is of great significance to study the structure property and self-assembly of amphiphilic block copolymer in order to effectively and efficiently design and prepare drug delivery systems. In this work, dissipative particle dynamics (DPD) simulation method was used to investigate the structure property and self-assembly ability of pH-responsive amphiphilic block copolymer poly(methyl methacrylatemethacrylic acid)poly(aminoethyl methacrylate) (poly(MMAMAA)PAEMA). The effects of different block ratios (hydrophilic PAEMA segment and pH-sensitive PMAA segment) in copolymer on self-assembly and drug loading capacity including drug distribution were extensively investigated.