Decision support model for selecting construction and demolition waste management alternatives: A life cycle-based approach.

Construction and demolition waste (C&DW) represents a pressing concern within the European Union, underscoring the urgent need for effective waste management strategies. The selection of these solutions constitutes a complex task, entailing the identification of efficient C&DW management strategies that balance appropriate practices, regulatory compliance, resource conservation, economic feasibility, and environmental considerations. LCA is widely utilized to assess environmental impact, yet the economic aspect has not been adequately incorporated into the LCA process in the field of C&DW management.

Industry 4.0 and life cycle assessment: Evaluation of the technology applications as an asset for the life cycle inventory.

Industry 4.0 technologies present transformative potential in data acquisition for production activities, promising to revolutionize the Life Cycle Inventory process. Despite acknowledging their utility in environmental impact analysis, a gap exists in understanding the specific applicability of these technologies to fulfill ISO 14044 criteria.

A Pediatric Patient with Severe Obstructive Sleep Apnea and Comorbid Depression and Substance Abuse.

Obstructive sleep apnea (OSA), depression, and substance abuse problems share similar symptomatology and have significant interplay. An underlying diagnosis of OSA can often be overlooked in patients with significant psychiatric illness and polysubstance use. Pediatric OSA is often associated with adenotonsillar hypertrophy and frequently requires surgical intervention for resolution of symptoms.

Consequential life cycle assessment of kraft lignin recovery with chemical recycling.

The recovery of kraft lignin from black liquor allows an increasing of the pulp production of a kraft mill (marginal tonnage) and at the same time provide a valuable material that can be used as energy or chemical feedstock. However, because lignin precipitation is an energy- and material-consuming process, the environmental consequences from a life cycle perspective are under discourse. The aim of this study is to investigate, through the application of consequential life cycle assessment, the potential environmental benefits of kraft lignin recovery and its subsequent use as an energy or chemical feedstock.

A life cycle assessment approach for nitrogen footprint quantification: the reactive nitrogen indicator.

Among the environmental issues that have recently catalyzed the attention of the scientific world, we must undoubtedly include the perturbation in the biogeochemical flows of nitrogen and phosphorus, which have been identified as one of the major risks on a global scale, also considering its social implications, since the use of macronutrients is essential to guarantee the food needs of the world population. In this context, there is a growing interest in the evaluation of the environmental impact related to this issue, particularly with regard to the effects of changes in the nitrogen cycle and the methods for quantifying them. In the latter field, several researches have recently been developed focusing on the indicator known as the nitrogen footprint, associated with the environmental releases of reactive nitrogen.

Combination of product environmental footprint method and eco-design process according to ISO 14006: The case of an Italian vinery.

To support the sustainable development of the primary sector, in line with green new deals emerging worldwide, eco-design of new agri-food products is a priority. The wine industry, due to its growing market, has matured the need to develop an approach for understanding the environmental impacts of its products and to develop strategies to reduce such impacts in a life cycle perspective. This study has a two-fold aim: presenting the development of a methodological proposal for the use of PEF and PEF-CR in the eco-design of wine products; testing its applicability in a case study in the wine sector.

Life cycle assessment applied to waste management in Italy: A mini-review of characteristics and methodological perspectives for local assessment.

Life cycle assessment (LCA) and related tools are commonly used to evaluate the potential environmental impacts of waste treatment scenarios. This manuscript presents a mini-review of studies published over the last 10 years in Italy and aims to investigate how life cycle thinking tools are applied to assess the environmental sustainability of local-level waste policies. Results reveal that different waste flows, technologies and policies have been investigated independently and in varying detail.

Covid19 impact screening of patients undergoing medication treatment for opioid use disorder.

Populations with addiction are considered at-risk for both medical and financial effects of the COVID19 outbreak. Patients receiving medication treatment for opioid use disorder (MOUD) were screened to assess need, vulnerability factors and potential clinical impact of the pandemic for referral and allocation of resources. : A 31-item quality improvement survey of COVID19-related factors (e.

Effects of Transcranial Direct Current Stimulation (tDCS) on Go/NoGo Performance Using Food and Non-Food Stimuli in Patients with Prader-Willi Syndrome.

Prader-Willi syndrome (PWS) is a neurodevelopmental genetic disorder characterized by multiple system involvement with hypotonia, poor suck with feeding difficulties, growth and other hormone deficiencies, intellectual disability, and behavioral problems with childhood onset of hyperphagia resulting in obesity, if not externally controlled. Transcranial direct current stimulation (tDCS) has been increasingly shown to modulate cognitive and behavioral processes in children and adults, including food-intake behaviors in patients with PWS. This study further reports the positive effects of brief tDCS sessions on Go/NoGo task performance involving food and non-food stimuli images, alterations in N2 brain amplitude, and genetic subgroup differences (maternal disomy 15, UPD; 15q11-q13 deletion, DEL) before and after tDCS as assessed by event-related potentials (ERPs) in 10 adults with PWS.

Life Cycle Assessment of Polyurethane Foams from Polyols Obtained through Chemical Recycling.

In this research, the results of the life cycle assessment of polyurethane (PUR) foams with different recycled polyol contents are presented. A methodological framework implementing laboratory activities directly into the life cycle assessment has been developed. Laboratory activities made the primary data related to the recycled polyol production available through the glycolysis of polyurethane scraps and the subsequent production and characterization of the foams.

Relationship Between Body Habitus and Aggression Subtypes Among Healthy Young Adults from the American Midwest.

This study examined associations between body habitus and functions of aggression, in a sample of 474 college students from the Midwestern region of the United States (age range = 18-25y; 73% Caucasian). Two instruments of aggression, the Reactive-Proactive Aggression Questionnaire from Dodge & Coie 1987 (DC) and Raine et al. 2006 (RPQ) were given as self-assessments.

Young adult predictors of alcohol dependence to age 53: a 44-year prospective cohort study of Danish men.

Aims: To examine if (1) there is a positive association between drinking volume in young men and life-time risk of alcohol dependence (AD) and (2) there are other associations between young adulthood factors and life-time risk of AD.

Design: Prospective cohort study of sons of fathers with alcohol use disorder (AUD) and matched low-risk controls without paternal AUD. Setting and participants A total of 204 men, who were assessed at baseline in 1979 at age 19-20 years, were followed through record linkage with Danish registers and consecutive psychiatric interviews at the ages of 33, 43 and 53 years.

Impostorism in American medical students during early clinical training: gender differences and intercorrelating factors.

Objectives: This study examined the incidence and severity of impostorism in third-year medical students as they transitioned from the preclinical to clinical phases of training.

Methods: A cross-sectional study was conducted in third-year medical students (N=215).  Respondents completed a voluntary, anonymous, 60-item survey that included the Clance Impostor Phenomenon Scale and the Perceived Stress Scale.

Impostorism in third-year medical students: an item analysis using the Clance impostor phenomenon scale.

Introduction: Impostorism, feelings of distrust in one's abilities and accomplishments despite evidence to the contrary, is frequent in medical students and negatively affects student wellness.

Methods: The aspects of impostorism that were most prevalent in medical students during the transition from the preclinical to clinical phases of their training were assessed using an anonymous, voluntary 60-item survey that included the Clance Impostor Phenomenon Scale (CIPS) and a 2-item burnout assessment administered in October-November 2018. Ratings of individual CIPS items were compared between items for the entire sample and in subpopulations of students.

Sex-Dimorphic Interactions of Genotype and Child Maltreatment Predispose College Students to Polysubstance Use.

Polysubstance use (PSU) is highly prevalent among college students. Recent evidence indicates that PSU is based on gene x environment (G×E) interactions, yet the specific biosocial factors underlying this problem remain elusive. We recently reported that lifetime use of tobacco and cannabis in college students is influenced by the interaction of the X-linked (monoamine oxidase A) gene and child maltreatment.

Kratom (Mitragyna speciosa): Friend or Foe?

Increased use of the opioid-related plant kratom as an alternative treatment for opioid withdrawal symptoms has raised concerns regarding its potential for abuse and severe adverse effects. A review of the literature was performed to characterize kratom's pharmacology, clinical efficacy, and adverse effects to increase understanding and evaluate potential use as an alternative treatment for opioid dependence. Kratom use initiated as self-medication for an opioid use disorder or pain syndrome in the absence of effective alternatives is associated with a risk of kratom dependence, withdrawal, and life-threatening toxicity.

Age Distribution, Comorbidities and Risk Factors for Thrombosis in Prader-Willi Syndrome.

Prader-Willi syndrome (PWS) is an imprinting disorder caused by lack of expression of the paternally inherited 15q11.2-q13 chromosome region. The risk of death from obesity-related complications can worsen with age, but survival trends are improving.

Diphenylbutylpiperidine Antipsychotic Drugs Inhibit Prolactin Receptor Signaling to Reduce Growth of Pancreatic Ductal Adenocarcinoma in Mice.

Background & Aims: Prolactin (PRL) signaling is up-regulated in hormone-responsive cancers. The PRL receptor (PRLR) is a class I cytokine receptor that signals via the Janus kinase (JAK)-signal transducer and activator of transcription and mitogen-activated protein kinase pathways to regulate cell proliferation, migration, stem cell features, and apoptosis. Patients with pancreatic ductal adenocarcinoma (PDAC) have high plasma levels of PRL.

Life Cycle Assessment Framework To Support the Design of Biobased Rigid Polyurethane Foams.

A methodological framework implementing laboratory activities and life cycle assessment is presented and applied to determine which parameters should be considered to develop biobased rigid polyurethane foams for thermal insulation with improved environmental performances when compared to their fossil counterparts. The framework was applied to six partially biobased (produced from bio-based polyols obtained from azelaic acid and/or lignin) and one fossil-based formulations. A comprehensive set of impact assessment categories was investigated including uncertainty and sensitivity analysis.

Venous Thromboembolism in Prader-Willi Syndrome: A Questionnaire Survey.

Prader-Willi Syndrome Association (USA) monitors the ongoing health and welfare of individuals with Prader-Willi syndrome (PWS) through active communication with members by membership surveys and data registries. Thromboembolism and blood clots have emerged in clinical studies as significant risk factors for injury and death in PWS. A 66-item questionnaire was developed by a panel of PWS medical and scientific experts, with input from Prader-Willi Syndrome Association (USA) leadership, so as to probe their membership on the frequency, risk, and protective factors for venous thromboembolism, pulmonary embolism, and related findings.

Time to remission analysis for major depressive disorder after repetitive transcranial magnetic stimulation (rTMS).

We previously examined the efficacy of rTMS for major depressive disorder in an applied clinical practice. Clinical response was related to severity of depression as well as the rTMS instrument utilized suggesting a relationship to instrument or magnetic field parameters and individual factors. The effectiveness of repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depressive disorder was further evaluated using Log-Rank statistics for time to remission outcomes.

Relationship between body mass and clinical response to repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder.

Repetitive transcranial magnetic stimulation (rTMS) has been proven to be efficacious in the treatment of Major Depressive Disorder (MDD). We previously examined the effectiveness of rTMS for MDD in an applied clinical setting, AwakeningsKC Clinical Neuroscience Institute (CNI) and found high remission rates for patients diagnosed with MDD following rTMS treatment. An unexpected relationship with body composition and rTMS unit was discovered.