[Complement componenets, C3 and factors B, in the blood of patients with acute ischemic stroke].

Several studies suggest that activation of compliment cascade contributes to the development of the inflammatory immune response in ischemic stroke and results in tissue injury by initiating apoptosis and necrosis. It is proposed that suppression of the compliment activation may have positive effect on stroke severity and outcome. However, the majority of data relevant to involvement of the compliment in the pathogenethic mechanisms of stroke have been obtained in animal models of stroke that does not allow to extrapolate these data to humans.

[Concentration and protein composition of circulating immune complexes in the blood of patients with schizophrenia and subjects with positive familial history of disease].

A comparative study of blood serum concentrations and pathogenic properties of circulating immune complexes (CIC), along with identification of their protein composition, was conducted in 45 patients with schizophrenia, 15 their healthy relatives and 39 normal controls. In patients and their relatives, mean concentration of small CIC was within the normal range, while concentrations of giant, large and middle CIC were higher than those of the controls (p<0.001).

[Characteristics of cyclodextrin production using cyclodextrin glucanotransferases of various groups of microorganisms].

Cyclodextrin glucanotransferases (CGTases; EC 2.4.1.

[New cyclomaltodextrin-glucanotransferases, produced by Bacillus macerans].

For the first time, microorganisms producing cyclomaltodextrin glucan transferases (CGT, EC 2.4.1.

[A diagnostic center in the practical public health system].

The authors describe a clinical diagnosis center working in close cooperation with a chair of therapy. Analysis of the activities of the center demonstrated the usefulness of medical divisions of such kind for practical health service, for it is at such diagnostic centers that profound examinations of patients, making use of present-day diagnostic methods, is possible at the preclinical stage. Such a possibility was offered to the residents of a large region who previously had to be hospitalized for this purpose.

[The role of the department of functional diagnosis in an interregional diagnostic center in improving the diagnostic process in cardiovascular diseases at the polyclinic stage].

Experience gained by one of the departments of the interregional diagnostic center (DC) provides evidence in favour of its setting up within the public health system. Owing to the department of functional diagnosis of the center, the outpatients can be examined skillfully, whereas previously only hospitalization was of help. Successful functioning of the department and perfection of its work require at least two conditions.

[Attitude of district physicians and the population toward measures regarding the prevention of ischemic heart disease].

The experience of the work on multifactorial prophylaxis of coronary heart disease performed on the basis of an urban out-patient center among 40-59-year-old males points to an inadequate response of the population to the primary (57 % after the mailing of 4 invitations) and repeated annual (50-60% of those who have had the primary examination) prophylactic examinations. Over 4 years, 22 % of patients with coronary heart disease and 32 % of patients with arterial hypertension refused to come for out-patient examinations. The number of responses was greater among individuals with risk factors of coronary heart disease.

[AMP-deaminase activity of rat brain nuclear and mitochondrial fractions].

It is established that purified nuclear and mitochondrial fractions of the rat brain possess a noticeable AMP-deaminase activity. ATP is an effective activator of AMP-deaminase in the both fractions, but this enzyme is also stimulated by hexokinase in the mitochondrial fraction. The ammonia production from ADP in the mitochondrial fraction is connected with the formation on ATP and AMP under the influence of myokinase and subsequent deamination of AMP by AMP-deaminase.

[Venous stasis and state of the microcirculatory bed in the synovial membranes].

Microcirculatory bed of the synovial membranes was investigated in experiments on dogs during venous stasis. Ligation of the femoral vein and circulatory disturbances led to the alteration of the microcirculatory bed of the synovial membranes, to the overfilling of the venules. Capillary walls became thinner and there developed swellings and protrusions.