Publications by authors named "Manuella Salm Coelho"

Article Synopsis
  • - The study explores bruxism's complex origins, noting that both genetic and non-genetic factors contribute to its development, but the role of genetic markers is still not well understood.
  • - Researchers analyzed 21 reports, including 16 original studies, focusing on genetic associations with sleep bruxism (SB) and awake bruxism (AB), identifying 15 significant genetic polymorphisms across 11 genes.
  • - Findings suggest specific genes associated with SB (like serotonergic and dopaminergic pathways) and AB (like ACTN3 and ANKK1), indicating potential genetic influences but highlighting the need for further research.
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Article Synopsis
  • Bruxism is a condition involving teeth clenching or grinding, often managed when adverse effects are felt, with botulinum toxin type A (BoNT-A) being a controversial treatment option.
  • This study aims to assess the effectiveness of BoNT-A for managing bruxism in adults by analyzing systematic reviews and conducting a comprehensive literature search across multiple databases.
  • The research will not require ethics approval and aims to publish findings in a high-impact journal, ensuring that results are effectively communicated to the broader scientific community.
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