Publications by authors named "Manuela Rocha de Menezes"
Article Synopsis
- Visceral leishmaniasis (VL) is a tropical disease caused by a parasite, influenced by environmental and genetic factors, particularly the genetic variations in cytokine genes.
- This systematic review and meta-analysis evaluated the impact of specific single nucleotide polymorphisms (SNPs) in interleukin genes on the susceptibility or resistance to VL, using data from multiple scientific databases.
- The analysis revealed significant associations between SNPs in the IFN-γ and IL-18 genes with VL, suggesting that these genetic variations could influence disease outcomes, while no significant links were found for IL-10 gene SNPs.
Glioblastoma (GBM) is the most common, aggressive and malignant type of glioma, with poor prognosis, despite advances in medical knowledge and technology. It's known that some microRNAs (miRNAs) can be dysregulated and associated with tumors. We aim to investigate miRNAs that may have a role as potential biomarkers in human glioblastoma.
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