Publications by authors named "Manuela Piccinino"

Article Synopsis
  • The study examines psychological vulnerability in Italian adolescents with polycystic ovarian syndrome (PCOS), particularly focusing on factors like body image, eating attitudes, and mood disorders.
  • Among the 128 participants, anxiety (63.1%) and depression (39.1%) were prevalent, alongside significant body image dissatisfaction (49.2%) and bulimic risk (41.4%), especially in those with obesity and insulin resistance.
  • The findings suggest that body image dissatisfaction mediates the relationship between anxiety and depression with bulimic risk, highlighting the need for a comprehensive biopsychosocial approach in managing PCOS-related psychological issues.
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Objectives: We investigated the attitudes to change the frequency of menstrual bleeding by using combined hormonal contraception (CHC). Personality characteristics were also explored.

Methods: We conducted a cross-sectional study in two university hospitals in northern Italy.

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Biological and psycho-relational factors contribute equally to the development of sexual symptoms and associated distress, a key element to diagnose female sexual dysfunctions (FSDs) in menopausal women. Consultation at midlife represents an optimal time to discuss sexual life, and healthcare providers have to be proactive in rising the conversation, as patients may not report their sexual concerns spontaneously. An accurate sexual history is essential to characterize the primary symptom, determine the impact on patient's quality of life and identify risk and precipitating factors.

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Background: Brain-derived neurotrophic factor (BDNF) is strongly related to hormonal networks and is modulated by hypothalamic activity.

Objective: To evaluate plasma BDNF concentration in patients with functional hypothalamic amenorrhea (FHA), with reference to the BDNF circadian rhythm and its relation with the cortisol (F) rhythm, and to assess whether the duration of amenorrhea might influence the BDNF:F ratio in FHA.

Design: This was an observational study evaluating 36 amenorrheic and 30 eumenorrheic women.

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