Publications by authors named "Manuela Konert"
Total Thrombus-Formation System in Patients with Peripheral Artery Disease.
Clin Appl Thromb Hemost
November 2024
Article Synopsis
- The Total Thrombus-formation Analysis System (T-TAS) is an automated tool designed to evaluate thrombus (blood clot) formation under simulated blood flow conditions, particularly in patients receiving antiplatelet therapy.
- This study examined T-TAS's effectiveness in detecting responses to dual antiplatelet therapy (DAPT) among 60 patients with peripheral artery disease (PAD) after a surgical procedure.
- Findings indicated that the platelet-chip (PL-chip) of T-TAS was able to identify low responders to DAPT more effectively than traditional aggregation tests, suggesting it could be a useful tool for monitoring treatment responses in PAD patients.
Background: Limited comparative data exist on different interventional strategies for endovascular revascularization of complex femoropopliteal interventions.
Objectives: In this study, the authors aimed to compare a stent-avoiding (SA) vs a stent-preferred (SP) strategy, promoting optimal lesion preparation and the use of drug-eluting technologies in both arms.
Methods: Within a prospective, multicenter, pilot study, 120 patients with symptomatic complex femoropopliteal lesions (Rutherford classification 2-4, mean lesion length 187.
Background: Preemptive selective embolization of aneurysm sac side branches (ASSBs) has been proposed to prevent type II endoleak after endovascular aortic aneurysm repair (EVAR). This study aimed to explore if an embolization strategy using microvascular plugs (MVP) reduces intervention time and radiation dose compared to platinum-fibered microcoils. Furthermore, the effectiveness of the devices in occluding the treated artery was assessed.
View Article and Find Full Text PDFPurpose: To evaluate the use of the GoBack-catheter (Upstream Peripheral Technologies) in complex revascularizations in lower limb arteries.
Materials And Methods: In this retrospective single-center study, the results of the first 100 consecutive patients including 101 limb-revascularizations, performed between May 2018 and July 2020 with the study device, were analyzed. In all cases, guidewire-crossing failed, and all lesions were chronic total occlusions (CTO), either de novo, reocclusions, or in-stent reocclusions.