Publications by authors named "Manuela Goncalves"

Article Synopsis
  • The importance of public health projects is emphasized due to ongoing pandemic crises and chronic health issues, making their success vital for community well-being.
  • A mixed-method study was conducted to identify the success factors that influence these public health projects, addressing a significant gap in existing literature.
  • The research culminated in a new model outlining these factors, offering valuable insights for project managers aiming to enhance the effectiveness of public health initiatives.
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Purpose: This study tested two hypotheses relating young athletes' sports motivations to parental behaviors and cognitive appraisal: (1) young athletes' motivation in sports is related to their parents' behavior; and (2) this relationship is mediated by cognitive appraisal, even after controlling for competitive level and sports records.

Method: This cross-sectional study included 673 young athletes and it measured the athletes' perceptions of parental behaviors, cognitive appraisal, and sports motivation.

Results: Structural equation modeling confirmed Hypothesis 1-the mother's behaviors accounted for 15 to 16% of the variance in sports motivation, and the father's behaviors accounted for 12 to 21% of the variance.

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Chitosomes are chitosan coated liposomes that represent an alternative to conventional liposomes since they present better stability and bioadhesivity. The aim of this work was to develop and evaluate the physico-chemical stability of melatonin (MEL)-loaded chitosomes as well as to compare their properties with that of MEL loaded liposomes. Structural characteristics of nanovesicles were also studied by dynamic light scattering and small angle X-ray scattering.

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The ovarian cystic teratoma is a rare cause of autoimmune haemolytic anaemia by warm antibodies, resistant to corticotherapy, with few case reports published in the medical literature. We present a case of a 45-year-old woman admitted to hospital due to general weakness. Laboratory studies revealed macrocytic anaemia, biochemical parameters of haemolysis and peripheral spherocytosis.

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ATP is an important excitatory neurotransmitter and adenosine acts as a neuromodulatory structure inhibiting neurotransmitters release in the central nervous system. Since the ecto-nucleotidase cascade that hydrolyzes ATP to adenosine is involved in the control of brain functions and previous studies realized in our laboratory have recently reported that acute administration of Arg decreases the NTPDase and 5'-nucleotidase activities of rat blood serum, in the present study we investigated the effect of arginine administration on NTPDase and 5'-nucleotidase activities by synaptosomes from hippocampus of rats. First, sixty-days-old rats were treated with a single or a triple intraperitoneal injection of arginine (0.

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