Immunohistochemical study of Ki67, CD34 and p53 expression in human tooth buds.

Aim Of The Study: Establishment of Ki67, p53 and CD34 expression in human tooth buds of different stages of odontogenetic development.

Materials And Methods: Tissue samples containing tooth buds were removed from the incisor areas of human fetuses in different stages of development (weeks 9-10, 12-13, 13-16, 21-24), and from the canine and molar areas of 21-24 weeks fetuses. The tissue fragments were fixed using formalin and were processed using common histological techniques with paraffin embedding.