Publications by authors named "Manuela Bedetta"

A new Italian intersociety position statement on the prevention of ophthalmia neonatorum was published in 2023. In this document, attention was paid to the indications for the screening of gonococcal and chlamydial infections during pregnancy according to the international and national guidelines for the prevention of sexually transmitted infections (STIs). We conducted an observational retrospective study to assess whether the current guidelines for the prevention of STIs are being followed correctly.

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Article Synopsis
  • Enterovirus (EV) and parechovirus (HPeV) are prevalent in newborns and are primary causes of aseptic meningitis in infants under 1 year.
  • A study compared 10 infants with HPeV meningitis to 8 with EV meningitis, revealing significantly higher serum C-reactive protein (CRP), white blood cell (WBC), and lymphocyte levels in the EV group.
  • Despite these differences, clinical symptoms alone cannot differentiate between the two infections, and real-time polymerase chain reaction remains the most reliable diagnostic method.
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Background: Preterm infants born between 33 and 35 weeks of gestational age (wGA) have been considered a "major underserved population" and ineligible to receive palivizumab (PLV), the only drug authorized to date for respiratory syncytial virus (RSV) prophylaxis, by current international guidelines. In Italy, such a vulnerable population is currently eligible for prophylaxis, and, in our region, specific risk factors are taken into consideration (SIN score) to target prophylaxis for those at highest risk. Whether the adoption of less or more restrictive eligibility criteria for PLV prophylaxis would translate into differences in bronchiolitis and hospitalization incidence is not known.

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We report the case of a 31-week gestational age neonate with Candida albicans sepsis and a hepatic abscess. Diagnosis relied on clinical and radiological signs of sepsis, liver function impairment and culture isolation of Candida spp. from sterile sites.

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