Long-Term Clinical and Hemodynamic Outcomes after Heart Transplantation in Patients Pre-Treated with Sildenafil.

Background: Elevated pulmonary vascular resistance remains a major problem for heart transplant (HT) candidate selection.

Objective: This study sought at assess the effect of pre-HT sildenafil administration in patients with fixed pulmonary hypertension.

Methods: This retrospective, single-center study included 300 consecutive, HT candidates treated between 2003 and 2013, in which 95 patients had fixed PH, and of these, 30 patients were treated with sildenafil and eventually received a transplant, forming Group A.

Heart Transplantation in Patients Older than 65 Years: Worthwhile or Wastage of Organs?

Background: Patients older than 65 years have traditionally not been considered candidates for heart transplantation. However, recent studies have shown similar survival. We evaluated immediate and medium-term results in patients older than 65 years compared with younger patients.