Biomathematical model to analyze the transmission dynamics of Covid-19: Case study, Santiago de Cali, Colombia.

The Covid-19 pandemic has challenged both the scientific community and government authorities in Colombia. Both sectors are collaborating to understand the transmission and spread of the virus and to establish control strategies. This study proposes a biomathematical model with difference equations to analyze the transmission of Covid-19 in Santiago de Cali from March 2020 to June 2022.

Multivariate analysis in data science for the geospatial distribution of the breast cancer mortality rate in Colombia.

This research is framed in the area of biomathematics and contributes to the epidemiological surveillance entities in Colombia to clarify how breast cancer mortality rate (BCM) is spatially distributed in relation to the forest area index (FA) and circulating vehicle index (CV). In this regard, the World Health Organization has highlighted the scarce generation of knowledge that relates mortality from tumor diseases to environmental factors. Quantitative methods based on geospatial data science are used with cross-sectional information from the 2018 census; it's found that the BCM in Colombia is not spatially randomly distributed, but follows cluster aggregation patterns.

Free will without consciousness?

Findings demonstrating decision-related neural activity preceding volitional actions have dominated the discussion about how science can inform the free will debate. These discussions have largely ignored studies suggesting that decisions might be influenced or biased by various unconscious processes. If these effects are indeed real, do they render subjects' decisions less free or even unfree? Here, we argue that, while unconscious influences on decision-making do not threaten the existence of free will in general, they provide important information about limitations on freedom in specific circumstances.

Flying Chameleons: A New Concept for Minimum-Deployment, Multiple-Target Tracking Drones.

In this paper, we aim to open up new perspectives in the field of autonomous aerial surveillance and target tracking systems, by exploring an alternative that, surprisingly, and to the best of the authors' knowledge, has not been addressed in that context by the research community thus far. It can be summarized by the following two questions. Under the scope of such applications, what are the implications and possibilities offered by mounting several steerable cameras onboard of each aerial agent? Second, how can optimization algorithms benefit from this new framework, in their attempt to provide more efficient and cost-effective solutions on these areas? The paper presents the idea as an additional degree of freedom to be exploited, which can enable more efficient alternatives in the deployment of such applications.

Towards a Post-Graduate Level Curriculum for Biodiversity Informatics. Perspectives from the Global Biodiversity Information Facility (GBIF) Community.

Biodiversity informatics is a new and evolving field, requiring efforts to develop capacity and a curriculum for this field of science. The main objective was to summarise the level of activity and the efforts towards developing biodiversity informatics curricula, for work-based training and/or academic teaching at universities, taking place within the Global Biodiversity Information Facility (GBIF) countries and its associated network. A survey approach was used to identify existing capacities and resources within the network.

Differential defense responses of tropical grasses to Mahanarva spectabilis (Hemiptera: Cercopidae) infestation.

The spittlebugs Mahanarva spectabilis economically challenges cattle production of neotropical regions, due to its voracious feeding on tropical grasses. Here, we evaluated biochemical responses of the interaction between M. spectabilis and the widely cultivated tropical grasses Brachiaria spp.

National Health Systems and COVID-19 Death Toll Doubling Time.

Coronavirus disease 2019 (COVID-19) has placed stress on all National Health Systems (NHSs) worldwide. Recent studies on the disease have evaluated different variables, namely, quarantine models, mitigation efforts, damage to mental health, mortality of the population with chronic diseases, diagnosis, use of masks and social distancing, and mortality based on age. This study focused on the four NHSs recognized by the WHO.

Reverse logistics models for the collection of plastic waste: A literature review.

To support the understanding of recycling models applied to plastics, the main objective of this work is to offer a literature review of the different reverse logistics (RL) models for collecting plastic waste (PW). The methodology used for processing the scientific literature was content analysis, using the google scholar search engine. The main keywords used were RL and PW.

Utilizing open-source platforms to build and deploy interactive patient-reported quality of life tracking tools for monitoring protocol adherence.

Purpose: Tracking patient-reported outcomes (PROs) and quality-of-life response rates is essential for clinical trials. Historically, rates are monitored through scheduled reports, which can require gathering, merging, and cleaning data from multiple databases. At the end of this process, if gaps are found, new data are entered and the cycle repeats, leaving a trail of reports that are not up-to-date or immediately accessible to the investigator.

Guidelines in Low and Middle Income Countries Paper 2: Quality assessment of Chilean guidelines: need for improvement in rigor, applicability, updating, and patients' inclusion.

Objectives: The Chilean health system mandates providers to ensure assistance under a guaranteed system, the Explicit Guarantees in Healthcare (EGH) program. The Health Ministry has developed clinical practice guidelines (CPGs), but independent assessment of their quality is lacking.

Study Design And Setting: We assessed all CPGs of the EGH program using Appraisal of Guidelines for Research & Evaluation II (AGREE II) tool for appraising quality, validity period, and last update.

Clinical and Economic Evaluation after Adopting Contingent Cell-Free DNA Screening for Fetal Trisomies in South Spain.

Introduction: Contingent cell-free (cf) DNA screening on the basis of the first-trimester combined test (FCT) results has emerged as a cost-effective strategy for screening of trisomy 21 (T21).

Objectives: To assess performance, patients' uptake, and cost of contingent cfDNA screening and to compare them with those of the established FCT.

Methods: This is a prospective cohort study including all singleton pregnancies attending to their FCT for screening of T21 at 2 university hospitals in South Spain.

Chaotic genetic algorithm and the effects of entropy in performance optimization.

This work proposes a new edge about the Chaotic Genetic Algorithm (CGA) and the importance of the entropy in the initial population. Inspired by chaos theory, the CGA uses chaotic maps to modify the stochastic parameters of Genetic Algorithm. The algorithm modifies the parameters of the initial population using chaotic series and then analyzes the entropy of such population.

Peer-to-Peer Sessions in Primary Care to Improve the Hepatitis B Detection Rate in Seville, Spain.

Introduction And Aim: The detection of hepatitis B virus (HBV) depends on primary care center activity. The present study aims to investigate the impact of peer-to-peer sessions with hepatologists on hepatitis B screening efficacy in primary care centers.

Material And Methods: Peer-to-peer one-hour sessions were scheduled to improve the screening program for HBV in Seville, Spain.

Neonatal Intestinal Obstruction Syndrome.

Neonatal intestinal obstruction is caused by an anatomical abnormality that produces bowel movement failure. Intestinal obstruction presents with three classic clinical signs: vomiting, abdominal distention, and failure to pass meconium. Intestinal obstruction is one of the most common causes for admitting a pediatric patient to the pediatric surgery unit in his or her first weeks of postnatal life.

Manipulation, oppression, and the deep self.

This essay considers various kinds of manipulation cases (local and global, dispositional and situational), and how Doris's Deep Self-style theory of responsibility fares in light of them. Agents acting with preferences adaptively formed under oppression are an especially interesting challenge for this sort of view, and the article considers what options may be available to Doris and others.

Autosomal recessive hypercholesterolemia in Spain.

Background And Aims: Autosomal recessive hypercholesterolemia (ARH) is a very rare disease, caused by mutations in LDL protein receptor adaptor 1 (LDLRAP1). It is characterized by high levels of low-density lipoprotein cholesterol (LDL-C) and increased risk of premature cardiovascular disease. We aimed to characterize ARH in Spain.

Measures Taken to Prevent Zika Virus Infection During Pregnancy - Puerto Rico, 2016.

Zika virus infection during pregnancy remains a serious health threat in Puerto Rico. Infection during pregnancy can cause microcephaly, brain abnormalities, and other severe birth defects (1). From January 1, 2016 through March 29, 2017, Puerto Rico reported approximately 3,300 pregnant women with laboratory evidence of possible Zika virus infection (2).

Monozygotic twinning after assisted reproductive technologies: a case report of asymmetric development and incidence during 19 years in an international group of in vitro fertilization clinics.

Objective: To describe a case of monozygotic twinning with asymmetric development following a single fresh embryo transfer as part of an intracytoplasmic sperm injection (ICSI) treatment. Secondarily, to report the incidence of monozygotic twinning at the IVI (Instituto Valenciano de Infertilidad) clinics.

Design: Case report.

Periodic breathing and oxygen supplementation in Chilean miners at high altitude (4200m).

Our objective was to determine the nocturnal ventilatory pattern and characterize the effect of oxygen enrichment on nocturnal ventilatory pattern and sleep quality in miners exposed to intermittent hypobaric hypoxia at 4200m. A total of 16 acclimatized miners were studied. Nocturnal ventilatory pattern (plethysmographic inductance), arterial oxygen saturation and heart rate (pulse oximetry) were performed in 9/16 subjects.

Hairy cell leukemia treated initially with purine analogs: a retrospective study of 107 patients from the Spanish Cooperative Group on Chronic Lymphocytic Leukemia (GELLC).

Abstract Purine analogs are highly effective in hairy cell leukemia (HCL) with response rates of 85%, but with many late relapses. We have retrospectively reviewed the clinical data from 107 patients treated with pentostatin (n = 27) or cladribine (n = 80), to investigate the long-term efficacy and to identify factors associated with the treatment-free interval (TFI). Complete remission and minimal residual disease (MRD) rates were similar in both groups.

Prolonged inflation of coronary angioplasty balloon as treatment for subocclusive dissection of the coronary sinus during implantation of a coronary sinus pacing lead.

Cardiac resynchronization therapy with biventricular stimulation is an accepted treatment procedure for patients with severe heart failure (NYHA class III/IV), low left ventricle ejection fraction, and left bundle branch block, in spite of optimal medical treatment (Smith, S. C. Jr, Feldman, T.

Role of endogenous interleukin-10 production and lipid peroxidation in patients with acute myocardial infarction treated with primary percutaneous transluminal coronary angioplasty, interleukin-10 and primary angioplasty.

Background: Currently available evidence suggests a potentially protective role for interleukin (IL)-10 in atherosclerosis. Reactive oxygen species, such as superoxide anion, hydrogen peroxide, peroxynitrite, and hydroxyl radical, seem to play a pivotal role in the pathogenesis of ischemia-reperfusion injury. The aim of this study was to assess whether a rise in lipid peroxidation (LPx), as malondialdehyde (MDA) and 4 hydroxyalkenal (4-HNE), during acute myocardial infarction (AMI) is associated with serum concentrations of IL-10.

Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction.

Objective: The purpose of this study was to assess whether serum levels of pregnancy-associated plasma protein A (PAPP-A) are elevated early in patients with acute myocardial infarction (AMI).

Design And Methods: We measured serum levels of PAPP-A in 80 patients with AMI and in 80 age-matched healthy control subjects. The mean (+/-SEM) time from onset of symptoms to blood sampling was 6.