ANALGESIC EFFICACY OF TRAMADOL/DEXKETOPROFEN VS IBUPROFEN AFTER IMPACTED LOWER THIRD MOLAR EXTRACTION: A RANDOMIZED CONTROLLED CLINICAL TRIAL.

Objective: Impacted third molar extraction is associated with acute moderate-to-severe pain for up to 48 hours post-surgery. This trial was designed to compare the analgesic effectiveness, swelling, and adverse events after impacted third molar surgery following multimodal therapy with 75 mg tramadol hydrochloride plus 25 mg dexketoprofen or monotherapy with 400 mg ibuprofen.

Methods: Seventy-two patients were randomly assigned to receiving ibuprofen (n = 36) or tramadol-dexketoprofen (n = 36).

Comparison of Implant Stability between Regenerated and Non-Regenerated Bone. A Prospective Cohort Study.

Implant stability is one of the main indicators of successful osseointegration. Although it has been measured in numerous studies, there has been little research on implant stability in regenerated bone. The study compares primary and secondary stability between implants placed in regenerated versus native bone and evaluates the influence of bone quality on the results.

Do perioperative antibiotics reduce complications of mandibular third molar removal? A double-blind randomized controlled clinical trial.

Objective: The aim of this study was to compare the effects of different antibiotic prophylaxis regimens versus placebo in relation to possible postoperative complications derived from the surgical extraction of impacted lower third molars.

Study Design: The final study sample of this double-blind randomized controlled trial comprised 92 Caucasian volunteers. Patients were assigned to 3 groups by using a randomization table.

Preoperative oral pregabalin for anxiety control: a systematic review.

Objective: The objective of this systematic review was to determine the effectiveness of preoperative oral pregabalin for anxiety control, the most effective dosage regimen, its impact on postoperative pain, and its adverse effects.

Materials And Methods: A search was conducted of PubMed/Medline and clinicaltrials.gov (National Library of Medicine, Washington, DC), Scopus, Web of Science, and Cochrane databases for studies published between January 2009 and November 2018, with no language restriction.

Double-blind, randomized controlled clinical trial on analgesic efficacy of local anesthetics articaine and bupivacaine after impacted third molar extraction.

Objective: The objective of this randomized controlled clinical trial (RCT) was to compare the effect of bupivacaine and articaine at habitual doses on pain intensity and the need for analgesics after lower third molar extraction.

Materials And Methods: The final study sample comprised 50 Caucasian volunteers (26 males and 24 females; age range, 18-30 years) undergoing scheduled surgical extraction of impacted lower third molar. A computer-generated random sequence was used to allocate participants to the articaine (4%) or bupivacaine (0.

Oral pregabalin for acute pain relief after cervicofacial surgery: a systematic review.

Objective: The objectives of this systematic review were to unify criteria on the effectiveness of oral pregabalin to treat acute post-operative pain after cervicofacial surgery, to establish the most effective dose regimens, and to determine its effect on rescue medicine consumption and its association with adverse effects.

Materials And Methods: PubMed/Medline (National Library of Medicine, Washington, DC), Scopus, Web of Science, and Cochrane databases were searched for studies in any language published between January 2000 and September 2016. The following question was posed, in accordance with PRISMA guidelines: Is oral pregabalin effective and safe for the relief of acute pain after cervicofacial surgery? The critical reading of the literature utilized a list of questions prepared by the CASPe Network, applying the Jadad scale for evaluation of the methodological quality of trials.

Oral pregabalin for postoperative pain relief after third molar extraction: a randomized controlled clinical trial.

Objectives: The aim of this randomized controlled clinical trial was to evaluate the efficacy and safety of pregabalin administered pre- and postoperatively in patients with pain and swelling due to the surgical removal of impacted lower third molars.

Materials And Methods: The final study sample comprised 60 volunteers (23 males and 37 females). Group 1 (n = 30) received 75 mg oral pregabalin 1 h before surgery and 1 h after surgery.

Risk factors associated with early implant failure: A 5-year retrospective clinical study.

Statement Of Problem: The replacement of lost teeth with dental implants is a widespread treatment whose associated problems are also frequently encountered. Nevertheless, the factors associated with early implant failure have not been well documented. Further analyses of the factors influencing osseointegration establishment are required to maximize the predictability of the procedure and minimize implant failures.

Long-Term Survival of Dental Implants with Different Prosthetic Loading Times in Healthy Patients: A 5-Year Retrospective Clinical Study.

Purpose: To compare survival rates among dental implants restored with immediate, early, and conventional loading protocols, also comparing between maxillary and mandibular implants, and to evaluate the influence of implant length and diameter and the type of prosthesis on treatment outcomes.

Materials And Methods: This retrospective cohort study initially included all 52 patients receiving dental implants between July 2006 and February 2008 at a private oral surgery clinic in Granada (Southern Spain). Clinical and radiographic examinations were performed, including periapical or panoramic radiographs, and incidences during completion of the restoration were recorded at 1 week, 3 months, 6 months, and at 1, 2, 3, 4, and 5 years.

Factors Affecting Dental Implant Stability Measured Using the Ostell Mentor Device: A Systematic Review.

Objectives: The aim of this study was to review the literature on factors that may affect dental implant stability as measured with the Ostell mentor device.

Materials And Methods: A systematic search of the literature was performed in Pubmed, Scopus, and Cochrane databases using dental implants, stability, and resonance frequency analysis as key words.

Results: The most relevant randomized controlled trials and clinical trials (n = 39) were selected from among 264 articles.

Bacterial contamination levels of autogenous bone particles collected by 3 different techniques for harvesting intraoral bone grafts.

Purpose: The aim of this study was to compare levels of bacterial contamination of autogenous bone collected when using low-speed drilling, a back-action chisel, and a bone filter.

Materials And Methods: Bone tissue samples were taken from 31 patients who underwent surgical extraction of their third lower molars. Before surgical removal of the molar, bone particles were collected by a low-speed drill or a back-action chisel.

Dental implant stability is influenced by implant diameter and localization and by the use of plasma rich in growth factors.

Purpose: The objective was to analyze the factors that influence the stability of dental implants at 12 weeks after implant placement as measured by resonance frequency analysis using the Osstell system.

Materials And Methods: This prospective clinical study was performed in 235 implants placed in 93 patients at the Oral Surgery and Implantology Clinic of the University of Granada. The gathered predictor variables were grouped into patient variables, implant variables, operative variables, and baseline implant stability quotient (ISQ).

Update on the use of corticosteroids in third molar surgery: systematic review of the literature.

Objectives: Third molar extraction produces inflammation, pain, and trismus, and different pharmacologic therapies have been evaluated for the minimization of postsurgical symptoms. The most frequently prescribed drugs are nonsteroidal anti-inflammatories, followed by steroids and opiates.

Material And Methods: A systematic search of the literature was carried out in PubMed, Scopus, MEDLINE, and Cochrane using steroid and third molar as key words.

Proliferation and osteogenic differentiation of osteoblast-like cells obtained from two techniques for harvesting intraoral bone grafts.

Objectives: The aims of our study were to verify the presence of viable osteoblasts in samples of bone tissue obtained by drilling or from cortico-cancellous bone blocks and to assess their growth and differentiation capacities.

Materials And Methods: Bone tissue samples were processed independently and cultured in Dulbecco's modified Eagle medium, in a CO2 incubator at 37 °C. The proliferative capacity of osteoblasts was determined by spectrophotometry (MTT) at 24 and 48 h of culture.

Effect of platelet-rich plasma on growth and antigenic profile of human osteoblasts and its clinical impact.

Purpose: In recent years, there has been widespread clinical use of platelet-rich plasma (PRP) to facilitate the regeneration of different tissues. However, few data are available on the effect of PRP on parameters other than cell growth. The aim of the present study was to evaluate the effect of PRP on the cell cycle, antigenic profile, and proliferation of primary cultured human osteoblasts.

Influence of cavity preparation technique (rotary vs. ultrasonic) on microleakage and marginal fit of six end-root filling materials.

Objectives: To evaluate in vitro the effect of cavity preparation with microburs and diamond-coated ultrasonic tips on the microleakage and marginal fit of six end-root filling materials. STUDY DESIGN. The following materials were assessed: amalgam (Amalcap), zinc oxide eugenol (IRM), glass ionomer (Vitrebond), compomer (Cavalite), mineral particle aggregate (MTA) and composite (Clearfil).

Factors related to survival from oral cancer in an Andalusian population sample (Spain).

Introduction: Approximately 3% of malignant tumors originate in the oral cavity. The majority are squamous cell carcinomas, and a small percentage, malignant tumors of the salivary glands, lymphoreticular diseases, bone tumors, melanomas, sarcomas, malignant odontogenic tumors and metastases of tumors from other locations. The prognosis of these pathologies depends on the size, infiltration, and site of the lesion, the presence or absence of metastatic spread, and to a certain degree the differentiation of the tumor.

Cylindrical dental implants with hydroxyapatite- and titanium plasma spray-coated surfaces: 5-year results.

Clinical follow-up was conducted on 127 cylindrical implants placed in 21 patients after 5 years of function: 75 implants were coated with titanium plasma spray (TPS) and 52 implants were coated with hydroxyapatite (HA). The aim of the study was to assess possible differences in clinical function and success rates for each implant type. Clinical and radiographic evaluations were conducted, and the periodontal indices of gingival bleeding, plaque, and calculus were measured.

A pilot study in the development of indices for predicting the clinical outcome of oral bone grafts.

Purpose: Bone grafting to repair osseous defects is widely used in dentistry, but little information on how to predict the clinical survival of grafted bone is currently available. As an initial step toward the establishment of formal criteria for predicting the clinical outcome of oral bone grafts, this pilot study sought to determine the relevance of adverse clinical and radiographic parameters as predictor variables for graft survival.

Materials And Methods: Eighty patients presenting with a variety of clinical conditions were treated with 83 oral bone grafts.

Post graduate training in oral surgery in Spain.

The objective of this investigative study is to provide information on the type of public postgraduate training in oral surgery currently being taught in Spain. A descriptive study is made relating to the theoretical and practical syllabuses of the different Masters, through questionnaires answered by students who had previously completed the postgraduate course. Later, a possible relationship between age, sex and previous training in dentistry or stomatology was explored.

Esthetic restoration with orthodontic traction and single-tooth implant: case report.

This case report describes the use of orthodontic traction to recover soft tissue lost around a maxillary right central incisor with major external root resorption associated with severe gingival recession. Traction of the residual root for 1 month produced a gingival appearance in harmony with the adjacent teeth. After the placement of an implant, a correct emergence profile was obtained, giving an optimal esthetic outcome.

Juvenile ossifying fibroma: a case study.

We present the case of an 8-year-old patient with a juvenile ossifying fibroma in the right mandibular angle and a radicular cyst in the left mandibular angle, which produced a major swelling at the level of the mandibular angles and prevented the correct eruption of the lower first molars. After the clinical and radiological (panoramic X-ray and dental scan of the mandible), the corresponding surgical treatment (cystectomy and remodelling) and histopathological study were carried out. Although juvenile ossifying fibroma is an uncommon clinical entity, its aggressive local behaviour and high recurrence rate mean that it is important to make an early diagnosis, apply the appropriate treatment and, especially, follow the patient up over the long term.

Update on immediate implant loading: a review of the literature.

The treatment of totally or partially edentulous patients with osseointegrated implants is an increasing part of daily dental practice. The greater aesthetic and functional demands made by these patients have created a constant pressure to reduce the waiting time before implants are loaded. In some cases, however, a shortening of the waiting period may compromise the osseointegration of the fixtures.

Phagocytosis and allogeneic T cell stimulation by cultured human osteoblast-like cells.

Background/aims: The antigen phenotype of human osteoblast-like cells suggests that they are related to other cellular populations and may also have immunologic functions in common.

Methods: Flow cytometry and transmission electron microscopy were used to show the phagocytotic activity of osteoblast-like cells in culture. The allogeneic stimulation of T cells by human osteoblast-like cells was determined by the measurement of T cell proliferation.

Antigenic phenotype of cultured human osteoblast-like cells.

Background/aims: Osteoblasts are classically considered to play an important role during bone tissue development, and to be involved in the formation of mineralized bone matrix. Recent reports have suggested that they can also exert some activities directly associated with the immune system (cytokine synthesis and antigen presentation). Moreover, some authors have found antigens on osteoblast-like cells normally expressed by other cells with a common origin in bone marrow.