Publications by authors named "Manuel Valdes-Navarro"

Purpose: To assess long-term effectiveness of rituximab therapy for refractory noninfectious uveitis affecting the posterior segment.

Methods: Retrospective case series. Patients diagnosed with recalcitrant noninfectious posterior uveitis who were treated with rituximab intravenous infusions between 2010 and 2015 were included.

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Article Synopsis
  • - Uveitis, particularly anterior uveitis, is a frequent and serious issue in kids with juvenile idiopathic arthritis, with up to 75% of childhood cases linked to this condition.
  • - Despite advances in detecting and treating uveitis, around 60% of affected patients may still face vision-threatening complications, such as cataracts and glaucoma.
  • - The paper reviews common eye complications related to uveitis in juvenile idiopathic arthritis and highlights recent diagnostic methods and treatment options available at the Massachusetts Eye Research and Surgery Institution.
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Purpose: Drug-induced uveitis is a well-known effect of ocular inflammation that has been reported with many medications. Pembrolizumab is a newer generation of the anti-programmed cell death-1 monoclonal antibodies that was recently approved by the Food and Drug Administration for the treatment of advanced melanoma. Immune-mediated adverse events involving different organs have been reported in recent literature in association with this drug.

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To compare the incidence of conjunctival infection with Chlamydia trachomatis in sexual partners of patients with newly diagnosed adult inclusion conjunctivitis (AIC) and a control group with healthy eyes. We also compare the observed signs and symptoms of conjunctival infection in patients with newly diagnosed AIC and their sexual partners. We performed a prospective comparative case-control study between patients with newly diagnosed AIC confirmed with direct fluorescent antibody (DFA) (n = 11), their sexual partners (n = 11), and a control group of healthy subjects (n = 11).

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