Publications by authors named "Manuel Sigfrido Rangel-Frausto"
Background: We report a meta-analysis of 4 identical time-series cohort studies of the impact of switching from use of open infusion containers (glass bottle, burette, or semirigid plastic bottle) to closed infusion containers (fully collapsible plastic containers) on central line-associated bloodstream infection (CLABSI) rates and all-cause intensive care unit (ICU) mortality in 15 adult ICUs in Argentina, Brazil, Italy, and Mexico.
Methods: All ICUs used open infusion containers for 6-12 months, followed by switching to closed containers. Patient characteristics, adherence to infection control practices, CLABSI rates, and ICU mortality during the 2 periods were compared by χ(2) test for each country, and the results were combined using meta-analysis.
Objective: To estimate the excess length of stay in an intensive care unit (ICU) due to a central line-associated bloodstream infection (CLABSI), using a multistate model that accounts for the timing of infection.
Design: A cohort of 3,560 patients followed up for 36,806 days in ICUs.
Setting: Eleven ICUs in 3 Latin American countries: Argentina, Brazil, and Mexico.
Attributable cost and length of stay for patients with central venous catheter-associated bloodstream infection in Mexico City intensive care units: a prospective, matched analysis.
Infect Control Hosp Epidemiol
January 2007
Article Synopsis
- The study aimed to evaluate the financial impact of central venous catheter-associated bloodstream infections (BSI) in ICUs in Mexico City, as there was a lack of previous information on this subject.
- It compared 55 patients with BSI to 55 without BSI, focusing on factors like ICU stay duration, hospital costs, and mortality rates over an 18-month period.
- Findings revealed that patients with BSI had a significantly longer ICU stay (6.1 extra days), incurred higher antibiotic costs (US $598), and faced greater overall hospital costs (US $11,591), highlighting the need for preventive measures to protect patients in Mexican hospitals.