Publications by authors named "Manuel RuiSS"

Purpose: To compare interindividual differences in visual performance of an advanced monofocal with a nondiffractive extended depth of focus intraocular lens (IOL) using a mini-monovision approach.

Design: Single-center, randomized, controlled, double-masked study.

Methods: In total, 48 patients (96 eyes) with bilateral age-related cataract were enrolled.

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Introduction: Several optical coherence tomography (OCT) biomarkers for postsurgical success among patients with idiopathic epiretinal membranes (iERMs) undergoing pars plana vitrectomy and membrane peeling have been described in the past. The aim of this study was to examine the remission of OCT biomarkers in patients with iERM after pars plana vitrectomy with membrane peeling 3 months and 1 year after surgery.

Methods: This prospective study included patients scheduled for pars plana vitrectomy with membrane peeling for iERM.

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Purpose: To compare the two most used digital alignment systems regarding precision, repeatability and loss of track.

Methods: 15 eyes of 15 patients older than 21 years with cataracts were included in this prospective study. The two systems were intraoperatively superimposed and recorded, and the alignment of the two displayed alignment axes was analysed regarding precision, repeatability and loss of track.

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Introduction: Nowadays, patients expect to be less spectacle dependent at all distances after cataract surgery. However, all intraocular lens (IOL) models that currently offer this function can also have negative visual effects. Aim of this study was therefore to compare the visual function performance of a novel and a conventional IOL solution for multifocality.

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Background: To compare the difference in rebubbling rates between patients undergoing Descemet membrane endothelial keratoplasty (DMEK) with endothelium-in using a standard IOL cartridge and those with endothelium-out DMEK utilizing a no-touch technique with borosilicate glass cartridge transplantation.

Methods: This retrospective study included all eyes that underwent preloaded endothelium-in or endothelium-out DMEK transplantation from June 2019 to December 2023 at the Hanusch Hospital, Vienna, Austria. All DMEKs were harvested, prepared and preloaded at the European Eye Bank of Venice, Italy.

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Purpose: To compare web-based, self-administered follow-up after cataract surgery to conventional face-to-face follow-up.

Setting: Eye clinics in the Netherlands, Austria, and Germany.

Design: Randomized controlled trial with an embedded method comparison study (ClinicalTrials.

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Purpose: To compare 4 different secondary intraocular lens (IOL) fixation techniques regarding the least required force to dislocate a scleral fixated 3-piece IOL in human corneoscleral donor tissue.

Design: Experimental laboratory investigation.

Methods: The least required dislocation force (LRDF) of 4 different secondary IOL fixation techniques, namely, the techniques using transscleral tunnels (TTs; as described by Scharioth), glued haptics (GHs; Agarwal), flanged haptics (FHs; Yamane), and bent haptic ends (BH; Behera/Bolz), were investigated using 40 three-piece IOLs (Sensar AR40) fixated to human scleral tissue.

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Introduction: Cataract surgery is a relatively safe procedure with satisfactory postoperative results in most patients. However, in rare cases severe complications can occur shortly after the intervention. Therefore, patients are advised to undergo an ophthalmological examination postoperatively, which should be performed as soon as possible in case of emergencies.

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Purpose: To measure the dislocation forces in relation to haptic material, flange size and needle used.

Setting: Hanusch Hospital, Vienna, Austria.

Design: Laboratory Investigation.

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Purpose: This study aimed to explore the concept of total keratometry (TK) by analyzing extensive international datasets representing diverse ethnic backgrounds. The primary objective was to quantify the disparities between traditional keratometry (K) and TK values in normal eyes and assess their impact on intraocular lens (IOL) power calculations using various formulas.

Design: Retrospective multicenter intra-instrument reliability analysis.

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Purpose: To investigate the flange properties of different iris hooks.

Setting: Vienna Institute for Research in Ocular Surgery (VIROS), Hanusch Hospital, Vienna, Austria.

Design: Laboratory study.

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Introduction: The objective of this study was to evaluate the prevalence of ocular surface damage assessed by corneal staining scores right after cataract surgery and whether it can be prevented using chitosan-N-acetylcysteine (C-NAC) eye drops.

Methods: We included patients scheduled for routine cataract surgery. Each patient was randomly assigned to one of three groups.

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Background: To comprehensively evaluate the agreement of component corneal aberrations from the newly updated wavefront analysis software of a swept-source optical coherence tomographer (SS-OCT) and a referential Placido-topography combined OCT device in elderly cataract patients.

Methods: Retrospective study including 103 eyes from 103 elderly patients scheduled for cataract surgery that were measured on the same day with a SS-OCT (Heidelberg Engineering, Germany) device and a Placido-topography combined OCT device (CSO, Italy). Anterior, total, and posterior corneal wavefront aberrations were evaluated for their mean differences and limits of agreement (LoA) via Bland-Altman plots.

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Purpose: To evaluate the effect of vectored thermal pulsation therapy (VTPT) on the repeatability of biometry readings of two different optical biometers in patients with meibomian gland dysfunction (MGD).

Methods: Patients affected by MGD were included in this prospective, randomized, controlled, investigator-masked study. One eye was randomized to VTPT (LipiFlow®, Johnson & Johnson), and the contralateral eye served as a control.

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Purpose: To evaluate the astigmatism-reducing effect of toric intraocular lenses (IOLs) for low amounts of corneal astigmatism.

Setting: Hanusch Hospital, Vienna, Austria.

Design: Randomized, masked, controlled trial with bilateral comparison.

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Purpose: To assess the diameter of different 30-gauge thin-wall needles and 3-piece intraocular lens (IOL) haptics readily used for the flanged-haptic intrascleral fixation technique.

Setting: Hanusch Hospital, Vienna, Austria.

Design: Laboratory investigation.

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Purpose: To examine the rotational stability of a new toric intraocular lens (IOL), the TECNIS Eyhance Toric II, over a course of 3 months.

Setting: Vienna Institute for Research in Ocular Surgery, Hanusch Hospital, Vienna, Austria.

Design: Prospective unmasked single-center study.

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Article Synopsis
  • A code-free deep learning system (CFDLS) was developed to classify high-resolution images of posterior capsule opacification (PCO) and distinguish between clinically significant and non-significant cases.
  • The model was trained and validated using a large dataset, showing high levels of reliability among expert observers and achieving excellent performance metrics (AUC of 0.99 internally and 0.97 externally).
  • The CFDLS demonstrated accuracy comparable to human experts, suggesting its potential as a decision support tool in clinical settings, warranting further investigation.
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A technique for achieving an optimal flange size with 5-0 polypropylene and 6-0 polypropylene used for flanged intrascleral intraocular lens fixation is described. Flange size in polypropylene sutures is dependent on heating length and independent of forceps grip during heating. It was identified that heating of 1 mm created the optimal flange size for a 5-0 polypropylene suture when used for a 27-gauge needle scleral tunnel and for a 6-0 polypropylene suture when used for a 30-gauge needle scleral tunnel.

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Cataract is the leading cause of blindness worldwide and surgery is the only option to treat the disease. Although the surgery is considered to be relatively safe, complications may occur in a subset of patients and access to ophthalmic care may be limited. Due to a growing and ageing population, an increase in cataract prevalence is expected and its management will become a socioeconomic challenge.

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Background: The aim of the present study was to compare macular hole closure rates of patients with small and medium-sized macular holes who underwent vitrectomy with internal limiting membrane (ILM) peeling combined with ILM flap transposition over the macular hole, compared with classic ILM peeling.

Methods: This prospective randomized trial was designed as a pilot study with two groups: ILM peeling with ILM flap transposition over the macular hole vs. classic ILM peeling.

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At the moment, cataract, which is the opacification of the eye's lens, can only be treated by surgery. In order to develop and test new pharmacological treatment strategies for the disease, there is a need for an appropriate in vitro model using ex vivo animal lenses. In this study, porcine lenses were incubated in either culture medium, glucose, triamcinolone acetonide, sodium chloride, hydrogen peroxide, sodium selenite, neutral buffered formalin, or were exposed to microwave heating to experimentally induce lens opacification.

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Background: The effect of air tamponade among patients undergoing vitrectomy with membrane peeling for removal of epiretinal membranes (ERM) is controversially discussed. The aim of the present study was to analyze differences in outcomes between air tamponade and balanced salt solution (BSS) in a study population with preoperative intraretinal cystoid changes.

Patients And Methods: This randomized study included patients scheduled for pars plana vitrectomy with membrane peeling owing to ERM and intraretinal cystoid changes.

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Purpose: To quantify intraoperative stress levels in cataract surgeons and investigate the relationship between intraoperative stress and surgeon experience.

Setting: Department of Ophthalmology, Hanusch Krankenhaus, Vienna, Austria.

Design: Prospective, observational case series.

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Purpose: To evaluate the comparability and variability of subjective refraction (SR), autorefraction (AR), and wavefront aberrometry (WA) in pseudophakic patients.

Setting: Hanusch Hospital, Vienna, Austria.

Design: Prospective study.

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