Botulinum toxin for treating unilateral apraxia of eyelid opening in a patient with congenital myotonia.

A 37-year-old female presented with severe apraxia of lid opening (ALO) affecting the right upper lid associated with Becker congenital myotonia (MC). The patient had a history of right upper lid ptosis for 25 years that was exacerbated over the previous month with severe incapacity to open her right eye. No other associated neurological or ophthalmic symptoms were observed.

Single surgical step for endoscopic surgery and orbital reconstruction of a silent sinus syndrome.

Silent sinus syndrome (SSS) is an uncommon disease characterised by enophthalmos, caused by ipsilateral maxillary sinus atelectasis. The diagnosis is clinical with radiological confirmation. The treatment has two objectives: to regulate the aeration of the maxillary sinus through achieving normal nasal cavity drainage and to restore the orbital architecture.

Autologous serum eye drops used to treat an ulcerated dermis-fat graft.

A 49-year-old woman with a contracted and keratinized anophthalmic socket underwent a dermis-fat graft for orbital augmentation. She presented with an early ulcer on the surface of the dermis, with inhibited conjunctival growth. There was no improvement after 1 month of conservative treatment.

Indolalkylamines derivatives as antioxidant and neuroprotective agents in an experimental model of Parkinson's disease.

Background: The neuroprotective effect of N-(2-propynyl)2-(5-benzyloxy-indol)methylamine (PF 9601N), a novel MAO B inhibitor, and its metabolite FA 72 on the human neuroblastoma SHSY5Y cell line lesioned with (300 microM) dopamine was assessed and compared with that of 1-deprenyl assayed at identical experimental conditions.

Material/methods: Using this experimental model, PF 961N showed a neuroprotective effect in a dose-dependent manner, and at a concentration of 10 pM a 20% recovery of cell viability was observed. However, the metabolite FA72 assayed under the same experimental conditions showed an increase in cell viability of nearly 50%.