Psychological characteristics associated with chemsex among men who have sex with men: Internalized homophobia, conscientiousness and serostatus as predictive factors.

Background: Although significant progress has been made in the rights of the LGBTQ+ community, even today this population still faces stigma and discrimination that impacts their mental health. In the case of men who have sex with men, it has been demonstrated that the use of drugs in a sexual context (chemsex) is one of the coping mechanisms and means of escape to deal with these situations.

Method: We assessed 284 native Spanish speakers' participants, 45,4 % were not engaged in sexualised drug use ( = 129) while 54,6 % were chemsex users ( = 155) using 18,7 % of them the injected via.

as a Complementary Treatment to Improve Symptomatology in Neurodegenerative Disease: A Systematic Review of Open Access Literature.

This systematic review addresses the use of ( in the symptomatological intervention of neurodegenerative disease. The existence of gut microbiota dysbiosis has been associated with systemic inflammatory processes present in neurodegenerative disease, creating the opportunity for new treatment strategies. This involves modifying the strains that constitute the gut microbiota to enhance synaptic function through the gut-brain axis.

Pre-Exposure Prophylaxis, Anxiety, Depression and Sexual SatisfactionAmong Men Who Have Sex With Men.

Background: Pre-exposure prophylaxis (PrEP) has been implemented as a prevention against HIV; however, its impact on mental health, sexual and life satisfaction has not been addressed.

Method: We assessed 114 HIV-negative participants from Spain with ages ranging from 19 to 58 years; 60.5% were PrEP users ( n = 69) and 39.

Targeting DNA Methylation in the Adult Brain through Diet.

Metabolism and nutrition have a significant role in epigenetic modifications such as DNA methylation, which can influence gene expression. Recently, it has been suggested that bioactive nutrients and gut microbiota can alter DNA methylation in the central nervous system (CNS) through the gut-brain axis, playing a crucial role in modulating CNS functions and, finally, behavior. Here, we will focus on the effect of metabolic signals in shaping brain DNA methylation during adulthood.