Unusual Presentation of Bladder Cancer in a Young Male With Significant Tattoo Exposure: A Case Report.

Recent studies have shown that polycyclic aromatic hydrocarbons (PAHs) can be found in commercial black tattoo inks raising suspicion of tattoo-related PAHs exposure to cancer risk. We present a case of a 27-year-old Hispanic nonsmoker male with bladder cancer (BC) following extensive tattoo sessions totaling over 100 hours. The patient was treated with transurethral resection of the bladder tumor (TURBT) and adjuvant intravesical Bacillus Calmette-Guerin (BCG) therapy.

Update on the Role of Glucocorticoid Signaling in Osteoblasts and Bone Marrow Adipocytes During Aging.

Purpose Of Review: Bone marrow adipose tissue (BMAT) in the skeleton likely plays a variety of physiological and pathophysiological roles that are not yet fully understood. In elucidating the complex relationship between bone and BMAT, glucocorticoids (GCs) are positioned to play a key role, as they have been implicated in the differentiation of bone marrow mesenchymal stem cells (BMSCs) between osteogenic and adipogenic lineages. The purpose of this review is to illuminate aspects of both endogenous and exogenous GC signaling, including the influence of GC receptors, in mechanisms of bone aging including relationships to BMAT.