The Role of Cell Cycle Arrest Biomarkers for Predicting Acute Kidney Injury in Critically Ill COVID-19 Patients: A Multicenter, Observational Study.

Objectives: Patients with COVID-19-associated acute respiratory distress syndrome (ARDS) have a high risk for developing acute kidney injury (AKI) which is associated with an increased risk of death and persistent renal failure. Early prediction of AKI is crucial in order to implement preventive strategies. The purpose of this study was to investigate the predictive performance of tissue inhibitor of metalloproteinases 2 and insulin like growth factor binding protein 7 (TIMP-2) × (IGFBP7) in critically ill patients with COVID-19-associated ARDS.

Decision Support System to Classify and Optimize the Energy Efficiency in Smart Buildings: A Data Analytics Approach.

In this paper, an intelligent data analysis method for modeling and optimizing energy efficiency in smart buildings through Data Analytics (DA) is proposed. The objective of this proposal is to provide a Decision Support System (DSS) able to support experts in quantifying and optimizing energy efficiency in smart buildings, as well as reveal insights that support the detection of anomalous behaviors in early stages. Firstly, historical data and Energy Efficiency Indicators (EEIs) of the building are analyzed to extract the knowledge from behavioral patterns of historical data of the building.

Surgical-orthodontic retreatment of a severe skeletal Class III malocclusion following an orthodontic camouflage.

Introduction: Class III malocclusions are some of the most difficult occlusal anomalies to be treated. Some patients with this condition may require orthognathic surgery, while others may be treated with dental camouflage. Proper patient assessment and selection remains critical in order to achieve favorable results.

Build Your Bioprocess on a Solid Strain-β-Carotene Production in Recombinant .

Robust fermentation performance of microbial cell factories is critical for successful scaling of a biotechnological process. From shake flask cultivations to industrial-scale bioreactors, consistent strain behavior is fundamental to achieve the production targets. To assert the importance of this feature, we evaluated the impact of the yeast strain design and construction method on process scalability -from shake flasks to bench-scale fed-batch fermentations- using two recombinant strains capable of producing β-carotene; SM14 and βcar1.

Influence of ligand encapsulation on cobalt-59 chemical-shift thermometry.

Thermometry magnetic resonance imaging (MRI) would provide a powerful noninvasive window into physiological temperature management. Cobalt-59 nuclear spins demonstrate exceptional temperature dependence of their NMR chemical shifts, yet the insight to control this dependence molecular design is lacking. We present the first systematic evidence that encapsulation of this spin system amplifies the temperature sensitivity.

Suitability of anodic stripping voltammetry for routine analysis of venous blood from raptors.

Lead (Pb) poisoning is a significant threat faced by raptors. Hence, rapid Pb diagnosis has become a priority during the admission of raptors in wildlife recovery centers, and bench-top analyzers, such as LeadCare II ®, are routinely employed for this purpose. However, this device has been designed for conducting analyses of human blood Pb levels (BLLs), and the validity of this methodology for whole blood from raptors has, to date, rarely been assessed.

Health and Disease Imprinted in the Time Variability of the Human Microbiome.

The animal microbiota (including the human microbiota) plays an important role in keeping the physiological status of the host healthy. Research seeks greater insight into whether changes in the composition and function of the microbiota are associated with disease. We analyzed published 16S rRNA and shotgun metagenomic sequencing (SMS) data pertaining to the gut microbiotas of 99 subjects monitored over time.

[Reducing chronic malnutrition among the disadvantaged populations to promote health and development].

This article advances theoretical and conceptual arguments to justify efforts to reduce chronic malnutrition as a basic component of any strategy for promoting health and development in countries with a high malnutrition prevalence. The arguments rest on four cardinal principles of contemporary social epidemiology, in whose framework reducing chronic malnutrition would be a key strategic component: the social determinants approach, the life course as the clinical-epidemiological paradigm, the concept of heredity and population health, and recognition of the family as a social determinant. Added to these are the close association between nutrition, health, and development, on the one hand, and the political significance of any strategy that makes the fight against chronic malnutrition the most visible focus of programmatic action.

Development and application of rapid assessment diet and physical activity indexes, which suggest high consumption of energy-dense foods and inadequate exercise among adolescents from 6 Latin American cities: a pilot study.

This study describes the development and application of a rapid assessment diet quality index (RADQI) and a rapid assessment physical activity index (RAPAI) to characterize the energy intake and expenditure patterns of 1279 Latin American adolescents. Secondary aims were to describe the strength of the relationships of energy intakes and expenditures with sex, socioeconomic status, body mass index, and city of residence and to identify the students' reasons for undertaking physical activity and the types of activities they most enjoyed. Participants were eighth and ninth grade students from Buenos Aires, Argentina; Guatemala City, Guatemala; Havana, Cuba; Lima, Peru; Panama City, Panama; and Santiago, Chile.

An exploration of the attitudinal and perceptual dimensions of body image among male and female adolescents from six Latin American cities.

Using survey methodology, this exploratory study examined the attitudinal and perceptual dimensions of body image among 1,272 eighth- and ninth-grade males and females from higher and lower socioeconomic backgrounds in Buenos Aires, Argentina (n = 195), Guatemala City, Guatemala (n = 212), Havana, Cuba (n = 213), Lima, Peru (n = 218), Panama City, Panama (n = 195), and Santiago, Chile (n = 239). The two dimensions of body image were assessed by showing the participants nine male and nine female silhouettes depicting body sizes ranging from extremely thin (#1) to extremely obese (#9). Approximately 50% of the male and female adolescents chose silhouette #3 as best depicting the attractive male body.

Malnutrition and poverty.

This paper is an attempt to discuss the problem of malnutrition within the framework of the global need for development and the challenges posed by the trends of neoliberalism and globalization. We argue that there is a two-way link between poverty and health in which nutrition plays an important role both as an active and as a mediating factor. Key concepts are exposed and expanded: (a) Development per se does not ensure better health; (b) unequal distribution of income has an independent effect on health indicators after adjusting for total income; (c) improving health can make an important contribution to reducing poverty; (d ) improving nutrition throughout the whole life course is an indispensable strategy for better health; (e) obesity has to be included amongst the most critical health problems, has different traits, and presents with different challenges in the developing world and in the industrialized countries.