Publications by authors named "Manuel M Weber"
Article Synopsis
- PSMA-targeted radioligand therapy is effective for advanced metastatic castration-resistant prostate cancer, but results vary among patients, prompting a study to use salivary glands as a reference for better patient stratification.
- The researchers calculated a tumor-to-salivary gland ratio (PSG score) from PET images of 237 men, categorizing them into high, intermediate, and low groups based on quantitative and visual assessments.
- The findings revealed that higher PSG scores correlated with better treatment outcomes, including a greater percentage of patients achieving over 50% prostate-specific antigen decline and longer PSA progression-free survival.
Article Synopsis
- Pulsed-field ablation (PFA) is a new way to treat a heart condition called atrial fibrillation without heating the tissue, unlike older methods.
- In a study with patients who had either PFA or cryoballoon ablation (CBA), they found that PFA caused less activation in certain cells in the heart compared to CBA.
- The results suggest that PFA may be safer and cause less damage, making it important for doctors to understand how different treatments work.
Visualization of thermal damage using Ga-FAPI-PET/CT after pulmonary vein isolation.
Eur J Nucl Med Mol Imaging
April 2022
Article Synopsis
- This study looks at a new imaging method called Ga-FAPI PET that helps see changes in heart tissue after a procedure to isolate pulmonary veins.
- It was tested on 12 patients who had their veins treated in different ways, with some showing more signs of tissue repair than others.
- The results suggest that one treatment method (CBA) may cause more significant healing effects than another (RFA), and future research could help better understand heart problems that might come back later.