Publications by authors named "Manuel M Alves"
This study examined test-retest reliability of single-breath lung diffusing capacity for nitric oxide (DLNO) and carbon monoxide (DLCO) during exercise. Sixteen healthy subjects (age 20-67 years) performed DLNO-DLCO tests during light and moderate intensity cycling exercise at 50% and 80% of individual anaerobic threshold (IAT). Primary endpoint was DLNO at 80% IAT.
View Article and Find Full Text PDFArticle Synopsis
- Colchicine, a drug that inhibits collagen synthesis, was tested for its effectiveness in treating alcoholic cirrhosis through a long-term, randomized, double-blind, placebo-controlled trial involving patients from 1989 to 1997.
- The study found no significant differences in survival rates, complications, or biochemical liver tests between the colchicine group and the placebo group, indicating that the drug doesn't provide substantial benefits in managing cirrhosis.
- Despite being well tolerated with no major side effects, the results suggest that colchicine does not alter the progression of alcoholic cirrhosis.