Publications by authors named "Manuel List"
Background: Over the past decades the use of assisted reproduction technology (ART) increased worldwide. ARTs are associated with an elevated risk for cardiovascular complications. However, a potential relation between subfertility/ARTs and the heart disease peripartum cardiomyopathy (PPCM) has not been systematically analyzed yet.
View Article and Find Full Text PDFAims: Peripartum cardiomyopathy (PPCM) is a pregnancy-associated cardiomyopathy that occurs in previously heart-healthy women towards the end of pregnancy or in the first months after delivery and is characterized by heart failure due to systolic dysfunction. The clinical course of PPCM differs between mild symptoms and severe forms with acute heart failure complicated by cardiogenic shock (CS). Treatment of CS complicating PPCM is challenging, as β-adrenergic receptor (β-AR) stimulation seems to be associated with progression of heart failure and adverse outcome.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to understand the relationship between cancer and heart failure in women who develop peripartum cardiomyopathy (PPCM) during or after pregnancy.
- It found that cancer prevalence is significantly higher in PPCM patients (8.9%) compared to age-matched women (0.59%), with many having prior cancer treatments that may affect heart recovery.
- Genetic testing revealed that a notable percentage of PPCM patients with cancer carry gene variants linked to both heart conditions and cancer risk, suggesting the need for screening in women with a cancer history during pregnancy.