Fingertip and Thumb Tip Wounds: Changing Algorithms for Sensation, Aesthetics, and Function.

Management of fingertip and thumb tip injuries has recently undergone substantial changes. The time-proven traditional armamentarium of local flaps has been expanded and replaced by a wide variety of flaps. Simultaneous with the development of new flaps, the conservative treatment of fingertip and thumb tip injuries with semiocclusive dressings has also become a more acceptable treatment for these injuries.

Management of thumb tip injuries.

The management of thumb tip injuries has undergone great changes in recent years. The traditional armamentarium of flaps has been expanded and replaced by a wide variety of flaps with more versatility and less donor side morbidity. Parallel to the development of new flaps, the conservative treatment of thumb tip injuries with semi-occlusive dressing has gained ground in the treatment of these injuries.

Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration.

Cutaneous regeneration utilizes paracrine feedback mechanisms to fine-tune the regulation of epidermal keratinocyte proliferation and migration. However, it is unknown how fibroblast-derived hepatocyte growth factor (HGF) affects these mutually exclusive processes in distinct cell populations. We here show that HGF stimulates the expression and phosphorylation of the microtubule-destabilizing factor stathmin in primary human keratinocytes.

CASE REPORT Febrile Ulceronecrotic Mucha-Habermann Disease.

Objective: Case report and review of the current literature about febrile ulceronecrotic Mucha-Habermann disease (FUMHD).

Methods: Review of our patient's medical records and of the current literature.

Results: The FUMHD is a rare and potentially lethal type of pityriasis lichenoides et varioliformis acuta.

Reverse homodigital dorsoradial flap for thumb soft tissue reconstruction: surgical technique.

A variety of local flaps are described for reconstruction of soft tissue defects of the thumb. Restored sensibility, low donor-site morbidity, full restoration of function and range of motion, and an acceptable aesthetic outcome are requirements in thumb reconstruction. Reverse homodigital dorsal radial flap of the thumb provides most of these requirements and allows for dependable coverage of radiopalmar or dorsal thumb defects without affecting other digits.