Purpose: To evaluate the effect of oral antioxidant supplementation (OAS) on primary open-angle glaucoma (POAG) over a 2-year follow-up period.
Patients And Methods: In this open-label, randomized controlled trial, 117 eyes of 117 patients with mild or moderate POAG and intraocular pressure under control with topical antiglaucoma medications were recruited and randomly divided into three groups according to supplementation: (1) OAS with (ICAPS R(®) - Alcon Laboratories, n = 26); (2) OAS without ω-3 fatty acids (OFTAN MACULA(®) - Laboratorios Esteve, n = 28); and (3) a control group without OAS (n = 63). They all underwent visual field (VF) tests (Humphrey 24-2) and scans using a Fourier-domain optical coherence tomography (FD-OCT) device (RTVue-100) at the beginning of the study and 2 years later.
Purpose: To compare central corneal thickness (CCT) results measured by Fourier-domain optical coherence tomography (FD-OCT) and ultrasound pachymetry (USP) in glaucomatous eyes.
Methods: In this prospective, observational cross-sectional study, 80 eyes of 80 patients with primary open-angle glaucoma (POAG) and no other ocular abnormality were selected: 28 were treated with 1 drug (subgroup 1), 32 with 2 drugs (subgroup 2), and 20 with 3 drugs (subgroup 3). CCT was measured by FD-OCT (RTVue OCT) and USP (Pachymeter Reichert IOPac).
Purpose: To compare the global indices and test duration as measured by Octopus 300 and Topcon SBP-3000 perimeters. To our knowledge, this is the first study performed in this way.
Methods: Eighty eyes of 40 glaucomatous and ocular hypertensive patients with previous perimetric experience had visual field tests with Octopus 300 (TOP strategy) and TOPCON SBP-3000.
Clin Ophthalmol
July 2011
Objective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region.
Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized.
Purpose: This study was designed to evaluate the effect of antioxidant supplementation on diabetic retinopathy (DR) over a 5-year follow-up period. To our knowledge, this is the first such clinical trial performed.
Methods: We recruited 105 type 2 diabetic patients with nonproliferative DR.
Purpose: To determine the effect of posterior capsular opacification (PCO) removal on anterior segment birefringence (ASB) and its influence on peripapillary retinal nerve fibre layer (RNFL) retardation measurements obtained by means of scanning laser polarimetry.
Methods: In this prospective interventional study, scanning laser polarimetry was performed using GDx variable corneal compensation on 26 eyes of 26 patients who developed clinically significant PCO (after uncomplicated cataract surgery and with no other ocular pathology) both before and between 1 and 4 weeks after Nd:YAG capsulotomy. Best-corrected visual acuity (BCVA), intraocular pressure, corneal polarization axis (CPA), corneal polarization magnitude (CPM) were compared using the Student t-test and Wilcoxon signed ranks test.
Purpose: Conjunctival provocation test (CPT) is a useful tool for the determination of the reagent in patients with allergic conjunctivitis. Our aim is to present an unusual reaction of ocular hypersensitivity to chlorobutanol by using this technique.
Methods: This case describes a 56-year-old woman who presented intense ocular pruritus and conjunctival hyperemia with each instillation of Colircusi Fluotest (Alcon, El Masnou, Spain).
Purpose: To evaluate the effect of posterior capsular opacification (PCO) on retinal nerve fiber layer (RNFL) retardation measurements obtained during scanning laser polarimetry (SLP). We are unaware of previous studies undertaken in this sense.
Methods: SLP was performed using GDx variable corneal compensation (VCC) on 28 eyes of 28 non-glaucomatous patients with clinically significant PCO, previous uneventful cataract surgery and no other ocular pathology, both before and after Nd:YAG capsulotomy.
Graefes Arch Clin Exp Ophthalmol
April 2006
Purpose: To illustrate the effect of posterior capsular opacification (PCO) on retinal nerve fiber layer (RNFL) retardation measurements obtained during scanning laser polarimetry (SLP).
Methods: SLP was performed using GDx VCC on three eyes of three non-glaucomatous patients with clinically significant PCO, before and after Nd:YAG capsulotomy.
Results: PCO removal by Nd:YAG capsulotomy was associated with marked variations in retardation map morphology and with apparent RNFL thinning.
Graefes Arch Clin Exp Ophthalmol
December 2005
Purpose: To present an unusual complication of posterior capsulotomy such as monocular diplopia and to discuss the importance of capsulotomy size.
Case Report: A 57-year old man came to our clinic complaining of horizontal monocular diplopia in his right eye for the past 3 days. The patient had undergone a Nd:YAG capsulotomy in this eye 3 weeks before.