Embarking on a cultural transformation within a school of nursing.

Schools of Nursing across the country are encountering fiscal, programmatic and leadership challenges exacerbated by chaos and fragmentation in health care systems. This article focuses on the transformation journey of the School of Nursing at the University of Minnesota highlighting the complex context of higher education, challenges faced, and strategies executed that focused on significant and sustained culture change. Recommendations are offered to enable all schools to embark on their own transformative journeys.

Magnetoelectric Nanodiscs Enable Wireless Transgene-Free Neuromodulation.

Deep-brain stimulation (DBS) with implanted electrodes revolutionized treatment of movement disorders and empowered neuroscience studies. Identifying less invasive alternatives to DBS may further extend its clinical and research applications. Nanomaterial-mediated transduction of magnetic fields into electric potentials offers an alternative to invasive DBS.

Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits.

Progress in understanding brain-viscera interoceptive signaling is hindered by a dearth of implantable devices suitable for probing both brain and peripheral organ neurophysiology during behavior. Here we describe multifunctional neural interfaces that combine the scalability and mechanical versatility of thermally drawn polymer-based fibers with the sophistication of microelectronic chips for organs as diverse as the brain and the gut. Our approach uses meters-long continuous fibers that can integrate light sources, electrodes, thermal sensors and microfluidic channels in a miniature footprint.

Endoscopic Facet Joint Denervation on the Lumbar Spine: A Retrospective Analysis.

Study Design: This single-center retrospective study analyzed patients with chronic low back pain (CLBP) who underwent endoscopic facet joint denervation (EFJD) between April 2018 and May 2019.

Purpose: This study was designed to investigate the effectiveness of EFJD in treating CLBP.

Overview Of Literature: CLBP is a challenging burden to healthcare systems worldwide.

Limited natural regeneration of unique Scalesia forest following invasive plant removal in Galapagos.

More than 60% of the flora of the Galapagos Islands is introduced and some of these species have become invasive, severely altering ecosystems. An example of an affected ecosystem is the Scalesia forest, originally dominated by the endemic giant daisy tree Scalesia pedunculata (Asteraceae). The remnant patches of this unique forest are increasingly being invaded by introduced plants, mainly by Rubus niveus (blackberry, Rosaceae).

Chronic Prostatitis/Chronic Pelvic Pain Syndrome Leads to Impaired Semen Parameters, Increased Sperm DNA Fragmentation and Unfavorable Changes of Sperm Protamine mRNA Ratio.

Background: Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a frequent disease affecting men of every age and accounting for a great number of consultations at urology departments. Previous studies suggested a negative impact of CP/CPPS on fertility. As increasing attention has been attributed to additional aspects, such as sperm DNA integrity and sperm protein alterations, besides the WHO standard semen analysis when assessing male fertility, in this prospective study, we aimed to further characterize the fertility status in CP/CPPS patients with a focus on these parameters.

Deletion of BDNF in Pax2 Lineage-Derived Interneuron Precursors in the Hindbrain Hampers the Proportion of Excitation/Inhibition, Learning, and Behavior.

Numerous studies indicate that deficits in the proper integration or migration of specific GABAergic precursor cells from the subpallium to the cortex can lead to severe cognitive dysfunctions and neurodevelopmental pathogenesis linked to intellectual disabilities. A different set of GABAergic precursors cells that express Pax2 migrate to hindbrain regions, targeting, for example auditory or somatosensory brainstem regions. We demonstrate that the absence of BDNF in Pax2-lineage descendants of KOs causes severe cognitive disabilities.

Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF.

Age-related decoupling of auditory nerve fibers from hair cells (cochlear synaptopathy) has been linked to temporal processing deficits and impaired speech recognition performance. The link between both is elusive. We have previously demonstrated that cochlear synaptopathy, if centrally compensated through enhanced input/output function (neural gain), can prevent age-dependent temporal discrimination loss.

A Functional K Channel from Tetraselmis Virus 1, a Member of the .

Potassium ion (K) channels have been observed in diverse viruses that infect eukaryotic marine and freshwater algae. However, experimental evidence for functional K channels among these alga-infecting viruses has thus far been restricted to members of the family which are large, double-stranded DNA viruses within the phylum . Recent sequencing projects revealed that alga-infecting members of , another family within this phylum, may also contain genes encoding K channels.

A History of Systemic Racism at the University of Minnesota School of Nursing.

A history of discrimination against racial and religious minorities at the University of Minnesota, maintained by powerful administrators who were subsequently honored with named buildings, was reflected in acts and patterns of racism in admissions and housing, within the School of Nursing. This article recounts well-documented examples of racial bias, particularly the story of Frances Mchie Rains, the first nurse of color to graduate from the University of Minnesota School of Nursing and a pioneer in overcoming racial barriers.

Lesbian, Gay, Bisexual, and Transgender People, and the Nursing Imperative.

This essay speaks to the legacy value of nurses' caring for all people, no matter how they feel about the person's values or lifestyle, including the current issues around gender identity and sexual orientation. This legacy is deeply imbedded in the moral ethics of nursing and supports the proposition that if there isn't caring, it isn't nursing.

From the Archive-A Brief Compendium of Curious and Peculiar Aspects of Nursing Resource Management.

The compendium of extraordinary operational skills required, the lack of recognition about the exact nature of nursing work, and deeply imbedded negative mind-sets result in staff nurses experiencing guilt and anger rather than the satisfaction of knowing they made a difference in someone's life because of the nursing care they gave. A change of mind-set from entitlement thinking to entrepreneurial thinking, with an emphasis on maximizing available resources, will empower nurses to understand that they have the right and the responsibility to decide what to do and what not to do when there is more work to do than time available.

Substance Use Disorders and the American Nurses Association .

Substance use disorder is a serious problem in nursing that is often invisible and not well understood or well handled. It tears at the social contract between nursing and society and disrupts the trust so essential to that contract. The American Nurses Association contains clear language about a nurse's duty to take action to protect patients and to ensure the impaired nurse gets assistance.

BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts and .

exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. However, how their differential transcription translates activity changes into long-lasting network changes is elusive. Aiming to trace specifically the network controlled by exon-IV and -VI derived BDNF during activity-dependent plasticity changes, we generated a transgenic reporter mouse for - - ), in which expression of exon-IV and -VI can be visualized by co-expression of CFP and YFP.

Visualizing BDNF Transcript Usage During Sound-Induced Memory Linked Plasticity.

Activity-dependent BDNF (brain-derived neurotrophic factor) expression is hypothesized to be a cue for the context-specificity of memory formation. So far, activity-dependent BDNF cannot be explicitly monitored independently of basal BDNF levels. We used the BLEV ( DNF- - ) reporter mouse to specifically detect activity-dependent usage of exon-IV and -VI promoters through bi-cistronic co-expression of CFP and YFP, respectively.

A Brief Compendium of Curious and Peculiar Aspects of Nursing Resource Management.

The compendium of extraordinary operational skills required, the lack of recognition about the exact nature of nursing work, and deeply imbedded negative mind-sets result in staff nurses experiencing guilt and anger rather than the satisfaction of knowing they made a difference in someone's life because of the nursing care they gave. A change of mind-set from entitlement thinking to entrepreneurial thinking, with an emphasis on maximizing available resources, will empower nurses to understand that they have the right and the responsibility to decide what to do and what not to do when there is more work to do than time available.

The glucocorticoid antagonist mifepristone attenuates sound-induced long-term deficits in auditory nerve response and central auditory processing in female rats.

Systemic corticosteroids have been the mainstay of treatment for various hearing disorders for more than 30 yr. Accordingly, numerous studies have described glucocorticoids (GCs) and stressors to be protective in the auditory organ against damage associated with a variety of health conditions, including noise exposure. Conversely, stressors are also predictive risk factors for hearing disorders.

The impact of primary nursing care pattern: Results from a before-after study.

Aims And Objectives: To explore the effect of "Primary Nursing" on nursing-sensitive patient outcomes, staff-related outcomes and organisation-related outcomes.

Background: Primary nursing is one example of a care pattern that has recently been implemented in many countries.

Design: Before-after study.

Bridging the Policy/Clinical Practice Divide: A Conversation With Parmeeth M. S. Atwal, JD, MSN, RN, MPH, FNP.

Marie Manthey, founder of Creative Health Care Management, interviews Parmeeth "Par" Atwal, whose first career included representing the National Association of Community Health Centers as an attorney, editor of a major health policy journal, and a senior position in the Office of the National Coordinator for Health Information Technology at the U.S. Department of Health and Human Services.

Distress Calls of a Fast-Flying Bat (Molossus molossus) Provoke Inspection Flights but Not Cooperative Mobbing.

Many birds and mammals produce distress calls when captured. Bats often approach speakers playing conspecific distress calls, which has led to the hypothesis that bat distress calls promote cooperative mobbing. An alternative explanation is that approaching bats are selfishly assessing predation risk.

Vegetation in Bangalore's Slums: Composition, Species Distribution, Density, Diversity, and History.

There is widespread acknowledgement of the need for biodiversity and greening to be part of urban sustainability efforts. Yet we know little about greenery in the context of urban poverty, particularly in slums, which constitute a significant challenge for inclusive development in many rapidly growing cities. We assessed the composition, density, diversity, and species distribution of vegetation in 44 slums of Bangalore, India, comparing these to published studies on vegetation diversity in other land-use categories.