Publications by authors named "Mansouri Nada"

Introduction: Glomangioma is an uncommon hypervascular tumor typically found in the extremities, with primary occurrences in the mediastinum being exceedingly rare.

Case Presentation: A 38-year-old male presented to our cardio-thoracic surgery department with chest pain. Chest computed tomography (CT) revealed a 45 mm posterior paravertebral right solidocystic mass, a finding confirmed by Magnetic resonance imaging (MRI) with a solidocystic mass in the posterior paravertebral right pleura suggesting a fibrous tumor exhibiting cystic degeneration.

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Article Synopsis
  • - Constitutional mismatch repair deficiency (CMMRD) syndrome is an autosomal recessive disorder linked to mutations in mismatch repair genes, increasing the risk of various cancers, particularly in early life.
  • - A case study presents a Tunisian patient with a specific mutation (c.1918C>A) who developed multiple aggressive cancers, surpassing typical age norms and displaying an unusually long survival time despite the severity of his condition.
  • - The report emphasizes the difficulties in determining the impact of genetic variants in CMMRD and highlights the diverse clinical presentations of the syndrome.
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Background: The aim of this study was to analyze PIK3CA mutations in exons 9 and 20 in breast cancers (BCs) and their association with clinicopathological characteristics.

Methods: Mutational analysis of PIK3CA exon 9 and 20 was performed by Sanger sequencing in 54 primary BCs of Tunisian women. The associations of PIK3CA mutations with clinicopathological characteristics were analyzed.

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Background: Breast cancer (BC) is the most frequent malignancy among women in Tunisia and Algeria. Clinical and pathological characteristics of this cancer among these populations are not widely reported. The aim of the study was to report clinical and pathological characteristics of women's BC in a Tunisian and Algerian series.

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Background: Spinal angiolipomas are rare benign tumors composed of mature adipose tissue and anomalous vascular channels. The sacral localization is extremely rare. To the best of our knowledge, there have been only two cases reported in the literature.

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SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is associated with flares of psoriasis in patients with well-documented disease. Both viral infection and medications used for treatment, like hydroxychloroquine, were incriminated. Herein, we report the case of a 25-year-old male patient who presented a first-onset guttate psoriasis following a COVID-19 infection.

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Introduction: Cervical synovial cysts are uncommon. They are most often responsible for a chronic clinical picture. Rarely, intracystic hemorrhage occurs, and may acutely present as radicular - or even spinal cord compression syndrome leading to irreversible neurological impairment.

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Multiple endocrine neoplasia type 1 is a rare autosomal inherited syndrome that affects a variety of endocrine tissues such as the parathyroid, endocrine pancreas, and anterior pituitary. Osseous complications are often misdiagnosed. We presented a case of a 46-year-old woman with pathological fractures of the lower limb.

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Squamous cell carcinoma of the prostate is rare and represents 0.5% to 1% of prostatic carcinomas. Transformation of prostatic adenocarcinoma into squamous cell carcinoma after LH-RH agonist intake has been reported in only 8 cases in the literature.

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Article Synopsis
  • Histological Gleason score is crucial for prostate cancer treatment, but there's often poor agreement between biopsy and final pathology results, with only a 43% concordance rate in a studied cohort.
  • The study evaluated 30 radical prostatectomy cases and found that 54% of the Gleason scores were upgraded upon surgery, significantly affecting treatment decisions.
  • Researchers noted that factors like age, PSA levels, and biopsy details did not significantly predict score upgrades, highlighting the need for better understanding of what causes this discordance to aid in patient care.
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The angiomyofibroblastoma-like tumor of the male genital tract is a rare benign tumor. A total of 34 cases have been reported in the literature. We herein report an exceptional case of solidocystic form in its paratesticular location, in a 79-year-old man.

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Background: Gastrointestinal stromal tumors - commonly called GISTs - are rare; yet, they represent an important type of mensenchymal tumors arising within the gastrointestinal tract. The acronym GIST was introduced in 1998 to define a well established pathological entity which bears a highly specific marker called KIT (CD117). Scientific interest for these tumors in recent years is mainly due to the progress in identification by immunohistochemistry and the advent of targeted molecular therapy.

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