Publications by authors named "Mansour O"

Objective: This study aims to evaluate the association between polycystic ovary syndrome (PCOS) phenotypes A and D with primary and secondary pregnancy outcomes among PCOS vs non-PCOS patients after in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI).

Methods: A retrospective cohort design using data of eligible women aged 20-40 years who had their first IVF treatment. The data were obtained from medical records.

View Article and Find Full Text PDF

Human parainfluenza viruses (hPIVs) are major contributors to respiratory tract infections in young children worldwide. Despite their global significance, genomic surveillance of hPIV1 and hPIV2 had not previously been conducted in Russia. This study aimed to develop a robust amplicon-based sequencing protocol for these viruses.

View Article and Find Full Text PDF

Feline panleukopenia (FPL) in cats is caused by either feline parvovirus (FPV) or canine parvovirus (CPV-2), which belong to the same species "Protoparvovirus carnivoran 1". While FPV is widely recognized as the principal cause of FPL, CPV-2 has been detected at a higher rate than FPV in sick cats in a recent Egyptian study. To assess this conflict, the present study aimed to determine which Protoparvovirus carnivoran 1 is commonly associated with FPL in Egyptian cats.

View Article and Find Full Text PDF

Introduction: Improper handling of biomedical waste causes health hazards. Dental practitioners and students as health care professionals should know about biomedical waste management from its generation to disposal. This will prevent associated risk and cross-infection.

View Article and Find Full Text PDF

Background: Heart failure (HF) is a global health challenge affecting millions, with significant variations in patient characteristics and outcomes based on ejection fraction. This study aimed to differentiate between HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF) with respect to patient characteristics, risk factors, comorbidities, and clinical outcomes, incorporating advanced machine learning models for mortality prediction.

Methodology: The study included 1861 HF patients from 21 centers in Jordan, categorized into HFrEF (EF <40%) and HFpEF (EF ≥ 50%) groups.

View Article and Find Full Text PDF

Background: Ehrlichiosis is a potentially fatal tick-borne disease that can progress to involve the central nervous system (CNS) (i.e., neuro-ehrlichiosis), particularly in cases where diagnosis and treatment are delayed.

View Article and Find Full Text PDF
Article Synopsis
  • * The review highlights various reasons for EVT underutilization, including challenges faced by healthcare providers, patients, and stakeholders in developing these services.
  • * It emphasizes the need for implementation research, strategic partnerships, and advocacy efforts to address these challenges and improve access to EVT.
View Article and Find Full Text PDF

This research proposes a highly sensitive and simple surface-enhanced Raman spectroscopy (SERS) assay for the detection of SARS-CoV-2 RNA using suitably designed probes specific for RdRp and N viral genes attached to a Raman marker. The sensitivity of the assay was optimized through precise adjustments to the conditions of immobilization and hybridization processes of the target RNA, including modifications to factors such as time and temperature. The assay achieved a remarkable sensitivity down to 58.

View Article and Find Full Text PDF

Introduction: Despite global progress in stroke care, challenges persist, especially in Low- and Middle-Income countries (LMIC). The Middle East and North Africa Stroke and Interventional Neurotherapies Organization (MENA-SINO) Stroke Program Accreditation Initiative aims to improve stroke care regionally.

Material & Method: A 2022 survey assessed stroke unit readiness in the Middle East and North Africa (MENA) + region, revealing significant regional disparities in stroke care between high-income and low-income countries.

View Article and Find Full Text PDF

Background: Medication use during pregnancy has increased in the United States despite the lack of safety data for many medications.

Objective: This study aimed to inform research priorities by examining trends in medication use during pregnancy and identifying gaps in safety information on the most commonly prescribed medications.

Study Design: We identified population-based cohorts of commercially (MarketScan 2011-2020) and publicly (Medicaid Analytic eXtract/Transformed Medicaid Statistical Information System Analytic Files 2011-2018) insured pregnancies ending in live birth from 2 health care utilization databases.

View Article and Find Full Text PDF

Background: Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in humans in 2012. Since then, 2605 cases and 937 associated deaths have been reported globally. Camels are the natural host for MERS-CoV and camel to human transmission has been documented.

View Article and Find Full Text PDF

Objective: Herein, we compare the features of neoplastic cancer cells in invasive ductal carcinoma (IDC) grade II and III patients to their corresponding normal cells both in breast and axillary lymph node (ALN) tissues.

Methods: A retrospective cohort of 70 female breast cancer patients enrolled between 2018 and 2020 at Medical Research Institute, Alexandria University, Egypt, was analyzed for clinicopathological features presentation. Fresh tiny pieces of breast tissue and its associated ALN tissues were then processed to investigate the morphological appearance by scanning electron microscopy.

View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to assess how cerebral microbleeds (CMBs) affect outcomes for stroke patients undergoing endovascular thrombectomy (EVT), focusing on functional independence and safety.
  • Using a systematic review approach, researchers analyzed four studies with 1,514 patients and found that the presence of CMBs significantly reduced the chances of achieving positive functional outcomes after EVT.
  • However, CMBs had no effect on successful revascularization rates, mortality, or the occurrence of various hemorrhagic complications, indicating a specific impact of CMBs on functional recovery rather than overall safety.
View Article and Find Full Text PDF

Background: The Coronavirus disease 2019 (COVID-19) pandemic was marked by an increase in diagnosis and treatment delays for a range of medical conditions. Yet the impact of the pandemic on the management of tick-borne diseases, which frequently manifest as an acute febrile illness similar to COVID-19, has not been well described.

Methods: In this retrospective cohort study of patients with suspected tick-borne disease attending the University of North Carolina Health facilities, we compared the timeliness of diagnosis and treatment in a "pre-COVID" period (March 2019 to February 2020) and a "post-COVID" period (March 2020 to February 2021).

View Article and Find Full Text PDF
Article Synopsis
  • - The study compared the effectiveness of post-transplant cyclophosphamide (PTCy) with methotrexate (MTX) and cyclosporine-A (CsA) in preventing graft-versus-host disease (GVHD) in patients receiving peripheral blood stem cell transplants from matched related donors.
  • - Among the 75 patients in each group, those receiving PTCy/CSA experienced significantly lower rates of chronic GVHD (13.4%) compared to those on MTX/CsA (38.6%).
  • - Overall survival and disease-free survival rates were similar for both groups after two years, indicating that while PTCy may offer benefits in reducing chronic GVHD, it does not significantly improve survival
View Article and Find Full Text PDF
Article Synopsis
  • - The World Stroke Organization launched the BEAT initiative to enhance collaboration between cardiologists and stroke physicians at major healthcare facilities, focusing on atrial fibrillation (AF) and poststroke cardiovascular complications.
  • - The pilot program included 10 sites across 8 countries and aimed to establish clinical pathways, regular meetings, and integrative roles within stroke teams, successfully achieving objectives in 9 out of 10 sites.
  • - Challenges included limited access to certain medications and diagnostic tools, but the initiative led to a more consistent approach in diagnosis and treatment, indicating potential for future programs to improve stroke care.
View Article and Find Full Text PDF
Article Synopsis
  • Endovascular thrombectomy (EVT) is the primary treatment for acute ischemic stroke due to large vessel occlusion, but only about one-third of patients achieve good outcomes, partly due to the "no-reflow" phenomenon affecting blood circulation.
  • A meta-analysis was conducted to evaluate the effectiveness of combining EVT with intra-arterial (IA) tissue plasminogen activator (tPA) in improving patient outcomes.
  • The analysis revealed no significant differences in successful recanalization, functional independence, or risk of symptomatic intracranial hemorrhage between the EVT alone and the EVT plus IA tPA groups, indicating the need for further randomized controlled trials.
View Article and Find Full Text PDF

Bone marrow embolism (BME) is likely a consequence of fractures in which pulmonary vessels are the most affected. However, some cases of BME were reported in the absence of trauma. Thus, a traumatic injury might not be necessary for developing BME.

View Article and Find Full Text PDF

Background: The management of intraosseous mandibular tumors in children is challenging. This study investigated clinical and pathological characteristics, surgical treatment, and outcome of pediatric benign intraosseous mandibular tumors.

Materials And Methods: A prospective study included patients under 18 years presenting with benign intraosseous mandibular tumors that were surgically managed.

View Article and Find Full Text PDF

Objectives: The triblock copolymer Pluronic® is widely used in the personal care industry, including sun protection, for its film-forming and solubilization capabilities. In this study, the effect of three commonly used organic UV filters (ethylhexyl methoxycinnamate [EMC], ethylhexyl triazone [EHT], and avobenzone [AVB]) on the structure of Pluronic P123 micelles was investigated.

Methods: The Pluronic P123 micelle structure has been investigated using dynamic surface tension, nuclear magnetic resonance (NMR) and small-angle neutron scattering (SANS).

View Article and Find Full Text PDF

Purpose: Because chronic kidney disease (CKD) is often under-coded as a diagnosis in claims data, we aimed to develop claims-based prediction models for CKD phenotypes determined by laboratory results in electronic health records (EHRs).

Patients And Methods: We linked EHR from two networks (used as training and validation cohorts, respectively) with Medicare claims data. The study cohort included individuals ≥65 years with a valid serum creatinine result in the EHR from 2007 to 2017, excluding those with end-stage kidney disease or on dialysis.

View Article and Find Full Text PDF