Mental Health Challenges in Cancer Survivors From Diverse Backgrounds During COVID-19 Pandemic: Insights From the All of Us Research Program.

Background: The COVID-19 pandemic exacerbated mental health challenges. This study aimed to investigate the mental health impact of the pandemic on cancer survivors from diverse backgrounds using the All of Us Research Program's COVID-19 Participant Experience (COPE) survey.

Methods: This analysis included respondents of the COPE survey with average depression, anxiety, and self-harm metrics computed for individuals completing multiple survey iterations.

Renal Artery Vasculopathy: Case Study and Literature Review.

Non-atherosclerotic renal artery vasculopathies are rare and can be caused by heterogenous group of diseases, some of which has bad prognosis. The literature addressing this rare group of disease is scarce. A single center analysis of all adult patients evaluated for renal artery disease including dissection, aneurysm, stenosis, vasculitis, thrombosis, irregularity, and renal infarct treated at our center, from January 2000 to April 2022.

Disproportionality Analysis of Hypotension-Related Adverse Drug Reactions Associated With Type 1a Selective Alpha-Blockers in VigiBase.

Purpose: Some evidence suggests no association between type 1a (T1a) selective alpha-blockers and hypotension-related adverse drug reactions (HR-ADRs), although safety concerns still exist. We sought to investigate the association of HR-ADRs with selective T1a blockers and identify at-risk groups.

Methods And Materials: We used disproportionality analysis to detect signals of HR-ADRs (dizziness, fainting, falls, and fractures) reported with selective T1a blocker use in VigiBase, a global database of individual case safety reports.

Redo Surgical Aortic Valve Replacement vs Valve-in-Valve Transcatheter Aortic Valve Replacement for Degenerated Bioprosthetic Valves.

Background: Valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) is associated with improved perioperative safety compared with redo surgical aortic valve replacement (redo-SAVR), but long-term outcomes remain uncertain. We therefore compare long-term outcomes of ViV-TAVR and redo-SAVR.

Methods: The study included 1:1 propensity score-matched Medicare beneficiaries with degenerated bioprosthetic valves admitted between September 29, 2011, and December 30, 2020, undergoing either redo-SAVR or ViV-TAVR.

Trend of ambulatory benign prostatic obstruction surgeries during COVID-19 pandemic.

Introduction: Benign prostatic obstruction (BPO) is one of the most common causes of male lower urinary tract symptoms. Some institutions routinely perform BPO surgeries in ambulatory setting, while others elect for overnight hospitalization. With the COVID-19 pandemic limiting resources and hospital space for elective surgery, we investigated the time trend of ambulatory BPO procedures performed around the COVID-19 outbreak.

Identification of Terpene Compositions in the Leaves and Inflorescences of Hybrid Species Using Headspace-Gas Chromatography/Mass Spectrometry.

Although cannabidiol and tetrahydrocannabinol in species exert their pharmacological effects via the endocannabinoid system, it is believed that other phytochemicals, particularly terpenes, can modulate therapeutic outcomes through the entourage effect. Therefore, to gain a better understanding of the pharmacological effects of , obtaining information on phytochemical compositions, including mono-, di-, and sesqui-terpenes in species is essential. Applying a sophisticated analytical method is indispensable.