Publications by authors named "Manshuk Ibrayeva"

The study investigates the phytochemical profile, antioxidant capacity, and antimicrobial activities of ethanol (ChL-EtOH) and ethyl acetate (ChL-EtOAc) extracts from L. (ChL) harvested in Kazakhstan. The ChL-EtOH extract exhibited higher total phenolic (267.

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A new compound, combrebisbibenzyl () as well as two sterols including stigmasterol () and 3---D-glucopyranoside of -sitosterol () and seven triterpenoids namely mollic acid (), oleanolic acid (), ursolic acid (), arjunglucoside I (, arjungenin (), bellericagenin B () and combregenin () were isolated from the root of . Compounds , and AcOEt and MeOH extracts exhibited moderate antioxidant activity with an IC value of 179.32, 185.

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Article Synopsis
  • Cancer is a diverse group of diseases causing about 10 million deaths globally each year, with current therapies like chemotherapy and radiation having significant side effects.
  • There is growing interest in alternative treatments, particularly natural compounds, such as Andrographolide from Andrographis paniculata, which shows promising anti-cancer properties by inhibiting various signaling pathways without major side effects.
  • Further research is necessary to fully understand Andrographolide's mechanisms, optimize its use, and confirm its effectiveness and safety in clinical settings.
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Over the years, many biological and synthetic agents have been explored and tested in attempts to halt the spread of cancer and/or cure it. Currently, several natural compounds have and are being considered in this regard. For example, paclitaxel is a potent anticancer drug that originates from the tree .

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(L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological data with their molecular mechanisms of action.

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