Background and objective Stroke-related deaths have been one of the major causes of death worldwide due to its rising risk factors. As a result, several people rely on YouTube as a great source of information on stroke without knowing the genuineness of the content. This study aims to assess the quality and reliability of the information on stroke uploaded on the YouTube platform using the Global Quality score (GQS) and DISCERN score (DS), respectively.
View Article and Find Full Text PDFBackground: Sensitive and specific detection of malarial parasites is crucial in controlling the significant malaria burden in the developing world. Also important is being able to identify life threatening Plasmodium falciparum malaria quickly and accurately to reduce malaria related mortality. Existing methods such as microscopy and rapid diagnostic tests (RDTs) have major shortcomings.
View Article and Find Full Text PDFAmphotericin and curcumin are known to form complexes with albumins individually. In-silico analysis shows that amphotericin B and curcumin have separate binding regions on human serum albumin and bovine serum albumin. The complex formed with albumin in the presence of both amphotericin and curcumin is water soluble, and it retains antifungal activity.
View Article and Find Full Text PDFIn silico docking analysis reported here suggests that insect cellular cytoskeletal beta-actin could be the target of Azadirachtin A (Aza-the principle bioactive compound of neem seeds). The best docking energy of -40.09 kcal/mol at 8.
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