Publications by authors named "Manoj Kumar Sabnani"
Article Synopsis
- Digital technologies and open innovation have led to the creation of virtual organizations, exemplified by the International Natural Product Sciences Taskforce (INPST), established in 2018 for collaboration in natural product research.
- The INPST utilized Twitter for a week-long networking event in June 2021, using the hashtag #INPST to facilitate interactions among participants.
- Analysis of the event revealed 6,036 tweets from 686 users, resulting in over 65 million impressions, highlighting Twitter's effectiveness for hosting international biomedical research discussions.
Quantification of low affinity binding interactions between natural killer cell inhibitory receptors and targeting ligands with a self-induced back-action actuated nanopore electrophoresis (SANE) sensor.
Sai Santosh Sasank Peri Manoj Kumar Sabnani Muhammad Usman Raza Elizabeth L Urquhart Soroush Ghaffari
Nanotechnology
January 2021
A plasmonic nanopore sensor enabling detection of bimodal optical and electrical molecular signatures was fabricated and tested for its ability to characterize low affinity ligand-receptor interactions. This plasmonic nanosensor uses self-induced back-action (SIBA) for optical trapping to enable SIBA-actuated nanopore electrophoresis (SANE) through a nanopore located immediately below the optical trap volume. A natural killer (NK) cell inhibitory receptor heterodimer molecule CD94/NKG2A was synthesized to target a specific peptide-presenting Qa-1 Qdm ligand as a simplified model of low-affinity interactions between immune cells and peptide-presenting cancer cells that occurs during cancer immunotherapy.
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