Publications by authors named "Manoj Kodigudla"

Purpose: Growing rods are the gold-standard for treatment of early onset scoliosis (EOS). However, these implanted rods experience frequent fractures, requiring additional surgery. A recent study by the U.

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Objective: To determine the effects of thoracic stiffness on mechanical stress in the lumbar spine during motion.

Methods: To evaluate the effect of preoperative thoracic flexibility, stiff and flexible spine models were created by changing the material properties of ligaments and discs in the thoracic spine. Total laminectomy was performed at L4/5 in stiff and flexible models.

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The primary objective was to compare the subsidence resistance properties of a novel 3D-printed spinal interbody titanium implant versus a predicate polymeric annular cage. We evaluated a 3D-printed spinal interbody fusion device that employs truss-based bio-architectural features to apply the snowshoe principle of line length contact to provide efficient load distribution across the implant/endplate interface as means of resisting implant subsidence. Devices were tested mechanically using synthetic bone blocks of differing densities (osteoporotic to normal) to determine the corresponding resistance to subsidence under compressive load.

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Background: The atlantoaxial complex contributes to significant neck movements, especially the axial rotation. Its instability is currently treated with various C1-C2 fusion techniques. This however, considerably hampers the neck movements and affects the quality of life; a C1-C2 motion preserving arthroplasty could potentially overcome this drawback.

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Article Synopsis
  • The study compares the biomechanical effects of two treatments for early-onset scoliosis: traditional growing rods (TGR) and a new spring distraction system (SDS).
  • The FEA models showed that while TGR had higher stress on rods and greater spinal growth advantages at 18 months, SDS experienced less stress overall and better IVD loading conditions.
  • The results suggest that the SDS may mitigate common issues like rod stress and disc height loss typically associated with TGR treatments.
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Background: This study evaluates the accuracy, biomechanical profile, and learning curve of the transverse process trajectory technique (TPT) compared to the straightforward (SF) and in-out-in (IOI) techniques. SF and IOI have been used for fixation in the thoracic spine. Although widely used, there are associated learning curves and symptomatic pedicular breaches.

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Article Synopsis
  • Growing rods are important for treating early-onset scoliosis but often suffer from rod fractures, leading to reoperations.
  • A new study used a patient-specific finite element model to simulate the surgical procedure and identify high stress regions on the rods.
  • Findings confirmed that the regions of high stress corresponded to common fracture sites previously identified in retrieval analyses, suggesting that these areas are prone to failure.*
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To evaluate the stability provided by a new bilateral fixation technique using an investigation for posterior lumbar segmental instrumentation. Experimental cadaver study. In this study, we propose an alternative technique for a posterior lumbar fixation technique called "inferior-oblique transdiscal fixation" (IOTF).

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Study Design: Randomized Biomechanical Cadaveric Study-Level II.

Objective: We aimed to elucidate that placing lateral lumbar interbody cages that span the stronger ring apophysis will require increasing loads for failure, decreasing rates of subsidence, regardless of bone density or endplate integrity.

Summary Of Background Data: There are several reports regarding the rates and grades of cage subsidence when utilizing the lateral lumbar interbody fusion technique.

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Adjacent-level disease is a common iatrogenic complication seen among patients undergoing spinal fusion for low back pain. This is attributed to the postsurgical differences in stiffness between the spinal levels, which result in abnormal forces, stress shielding, and hypermobility at the adjacent levels. In addition, as most patients undergoing these surgeries are osteoporotic, screw loosening at the index level is a complication that commonly accompanies adjacent-level disease.

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Background: Previous studies in humans have reported that the dimensions of the intervertebral foramina change significantly with movement of the spine. Cervical spondylomyelopathy (CSM) in dogs is characterized by dynamic and static compressions of the neural components, leading to variable degrees of neurologic deficits and neck pain. Studies suggest that intervertebral foraminal stenosis has implications in the pathogenesis of CSM.

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Objective: To quantify changes in the diameter of the vertebral canal with flexion and extension in the cervical vertebral column.

Study Design: Cadaveric biomechanical study.

Sample Population: Cadaveric canine cervical vertebral column (n = 16 dogs).

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