Synthesis, structural characterisation, and anticancer potential of mono and dinuclear Pd(II) complexes of -(2-pyridyl)thiourea.

Cancer is a prominent global cause of mortality. Palladium complexes have the potential to serve as effective anticancer and pharmacological agents, offering a viable alternative to platinum medications. This work focused on the development of a new thiolato-bridged dinuclear [Pd(M3MPyThU)Cl]2 and mononuclear palladium [Pd(M3MPyThU)2] complexes containing 1-methyl-3-(3-methylpyridin-2-yl) thiourea (HM3MPyThU) ligand.

Copper-Based Electrochemical Sensor Derived from Thiosemicarbazide for Selective Detection of Neurotransmitter Dopamine.

This paper presents the synthesis of the ligand 1-picolinoyl-4-cyclohexyl-3-thiosemicarbazide (Hpctc) and new metal complexes [Ni(Hpctc)] (), [Cu(Hpctc)Cl] (), and [Cd(Hpctc)] (). The synthesized metal complexes were precisely characterized using single crystal X-ray diffraction (SC-XRD). In addition, complexes - were also characterized by UV-vis, fluorescence, and infrared spectroscopy.

Co-catalysed synthesis of -(4-meth-oxy-phen-yl)-5-(pyridin-4-yl)-1,3,4-oxa-diazol-2-amine hemi-hydro-chloride monohydrate.

The title compound, CHNO·0.5HCl·HO or H(CHNO) ·Cl·2HO, arose from the unexpected cyclization of isonicotinoyl--phenyl hydrazine carbo-thio-amide catalysed by cobalt(II) acetate. The organic mol-ecule is almost planar and a symmetric N⋯H⋯N hydrogen bond links two of them together, with the H atom lying on a crystallographic twofold axis.

Evaluation of different regression models for detection of adulteration of mustard and canola oil with argemone oil using fluorescence spectroscopy coupled with chemometrics.

Mustard and canola oils are commonly used cooking oils in Asian countries such as India, Nepal, and Bangladesh, making them prone to adulteration. Argemone is a well-known adulterant of mustard oil, and its alkaloid sanguinarine has been linked with health conditions such as glaucoma and dropsy. Utilising a non-destructive spectroscopic method coupled with a chemometric approach can serve better for the detection of adulterants.

Cobalt (III) complex exerts anti-cancer effects on T cell lymphoma through induction of cell cycle arrest and promotion of apoptosis.

Purpose: Cobalt-based compounds are emerging as a non-platinum-based anti-cancer effective therapeutic agent. However, there is a limited study regarding the therapeutic efficacy of Cobalt-based drugs against Non-Hodgkin's Lymphoma (NHLs) such as T cell lymphoma. Therefore, in the present study we investigated the anti-tumor role of cobalt(III) complex [Co(ptsm)NH(o-phen)]·CHOH on Dalton's Lymphoma (DL) cells.

Advances in protein misfolding, amyloidosis and its correlation with human diseases.

Protein aggregation, their mechanisms and trends in the field of neurodegenerative diseases is still far from completely being decoded. It is mainly attributed to the complexity surrounding the interaction between proteins which includes various regulatory mechanisms involved with the presentation of abnormal conditions. Although most proteins are functional in their soluble form, they have also been reported to convert themselves into insoluble aggregates under certain conditions naturally.

Crystal structure of N'-[bis-(ethyl-sulfan-yl)methyl-idene]-2-hy-droxy-4-meth-oxy-benzohydrazide.

In the title compound, C13H18N2O3S2, the amide group is in the plane of the -benzoyl ring with a C-N-N-C torsion angle of 177.63 (12)°. The two di-thio-ate groups are in an anti conformation [torsion angles = 173.

Crystal structure of 5-(furan-2-yl)-N-phenyl-1,3,4-oxa-diazol-2-amine.

The title compound, C12H9N3O2, was obtained as a cyclized oxa-diazole derivative from substituted thio-semicarbazide in the presence of manganese(II) acetate. The furan ring is disordered over two orientations, with occupancies of 0.76 (2) and 0.