Publications by authors named "Manoharan Geetha"
Aims: To report trends in antibiotic resistance in cases of bacterial keratitis from a large eye hospital in South India.
Methods: In this retrospective cross-sectional study, the microbiology laboratory records of patients with infectious keratitis diagnosed at an eye hospital in South India from 2002 to 2013 were reviewed to determine the proportion with antibiotic non-susceptibility.
Results: 3685 bacterial isolates had susceptibility testing performed over the 12-year period.
Objective: To assess the trends in microbiological organisms identified from corneal scrapings from patients with infectious keratitis at a tertiary care medical centre in South India.
Methods: We reviewed the records of the microbiology laboratory at Aravind Eye Hospital in Madurai, India, from 2002 until 2012. We identified the microbiological causes of all corneal ulcers from the culture and smear results, and assessed for trends in bacterial and fungal keratitis over time.
Article Synopsis
- The study examines 13 patients who developed Burkholderia cepacia complex endophthalmitis after cataract surgery, highlighting the clinical outcomes and sources of infection.
- The findings revealed that all vitreous samples tested positive for B. cepacia, which was also found in contaminated topical anaesthetic eye drops, indicating a significant source of infection.
- Despite the serious nature of the infection, 69% of the patients achieved a final visual acuity of 6/60 or better, but some were left with very limited vision, emphasizing the need for vigilance in sterile procedures.
Purpose: To assess the association between minimum inhibitory concentration (MIC) and clinical outcomes in a fungal keratitis clinical trial.
Design: Experimental study using data from a randomized comparative trial.
Participants: Of the 323 patients enrolled in the trial, we were able to obtain MIC values from 221 patients with monocular fungal keratitis.
Purpose: To describe the minimum inhibitory concentration (MIC) of fungal isolates to natamycin and voriconazole, and to compare these MICs to previous ocular susceptibility studies.
Design: Experimental laboratory study using isolates from a randomized clinical trial.
Methods: The Mycotic Ulcer Treatment Trial I was a randomized, double-masked, multicenter trial comparing topical natamycin and voriconazole for fungal keratitis treatment.
Objective: To analyze the relationship between fluoroquinolone use at presentation and minimum inhibitory concentration in bacterial keratitis.
Methods: The Steroids for Corneal Ulcers Trial was a randomized, double-masked, placebo-controlled trial assessing the effect of adjunctive topical corticosteroid treatment on outcomes in bacterial keratitis. After presentation, all patients were treated with moxifloxacin hydrochloride, 0.
We report a case of an agricultural worker presenting with corneal infiltrate following ocular injury with a rice husk. On examination, a superficial corneal foreign body was removed and sent for culture, which grew Pantoea ananatis. This is, to our knowledge, the first clinical case report of Pantoea ananatis causing corneal infiltrate.
View Article and Find Full Text PDF